Results 31 to 40 of about 190,539 (312)

Predicting Kidney Transplant Survival using Multiple Feature Representations for HLAs [PDF]

open access: yesProceedings of the 19th International Conference on Artificial Intelligence in Medicine (2021) 51-60, 2021
Kidney transplantation can significantly enhance living standards for people suffering from end-stage renal disease. A significant factor that affects graft survival time (the time until the transplant fails and the patient requires another transplant) for kidney transplantation is the compatibility of the Human Leukocyte Antigens (HLAs) between the ...
arxiv  

Early onset of graft glomerulopathy in a patient with post-transplant diabetes mellitus after renal transplantation: a case report

open access: yesBMC Nephrology, 2018
Background Post-transplant diabetes mellitus (PTDM) is an emerging problem in kidney transplantation, representing an important risk factor for kidney function loss.
Marilena Gregorini   +4 more
doaj   +1 more source

Predicting Dosage of Immunosuppressant Drugs After Kidney Transplantation Using Machine Learning [PDF]

open access: yesarXiv, 2023
While kidney transplants are seen as the best treatment option for patients with end-stage renal disease and kidney failure, the organ's health depends on the dosage of immunosuppressant drugs post-transplantation. Due to the dosage variance based on each patient's unique physiology, nephrologists face numerous difficulties when determining the precise
arxiv  

Perceptions of Illness Severity, Treatment Goals, and Life Expectancy: The ePISTLE Study

open access: yesKidney International Reports, 2021
Introduction: A better understanding of factors influencing perceived life expectancy (PLE), interactions between patient prognostic beliefs, experiences of illness, and treatment behavior is urgently needed.
Hannah K.S. Beckwith   +10 more
doaj  

Time-dependent Clearance of Cyclosporine in Adult Renal Transplant Recipients: A Population Pharmacokinetic Perspective [PDF]

open access: yesarXiv, 2021
Aim The pharmacokinetic (PK) properties of cyclosporine (CsA) in renal transplant recipients are patient- and time-dependent. Knowledge of this time-related variability is necessary to maintain or achieve CsA target exposure. Here, we aimed to identify factors explaining variabilities in CsA PK properties and characterise time-dependent clearance (CL/F)
arxiv  

A phase 1b study of venetoclax and azacitidine combination in patients with relapsed or refractory myelodysplastic syndromes

open access: yesAmerican Journal of Hematology, Volume 98, Issue 2, Page 272-281, February 2023., 2023
Abstract Patients with relapsed/refractory (R/R) higher‐risk myelodysplastic syndromes (MDS) have a dismal median overall survival (OS) after failing hypomethylating agent (HMA) treatment. There is no standard of care for patients after HMA therapy failure; hence, there is a critical need for effective therapeutic strategies.
Amer M. Zeidan   +18 more
wiley   +1 more source

Evaluation of an automated choroid segmentation algorithm in a longitudinal kidney donor and recipient cohort [PDF]

open access: yesarXiv, 2023
Purpose: To evaluate the performance of an automated choroid segmentation algorithm in optical coherence tomography (OCT) data using a longitudinal kidney donor and recipient cohort. Methods: We assessed 22 donors and 23 patients requiring renal transplantation over up to 1 year post-transplant.
arxiv  

Rejection-proof Kidney Exchange Mechanisms [PDF]

open access: yesarXiv, 2022
Kidney exchange programs (KEPs) form an innovative approach to increasing the donor pool through allowing the participation of renal patients together with a willing but incompatible donor. The aim of a KEP is to identify groups of incompatible donor-recipient pairs that could exchange donors leading to feasible transplants.
arxiv  

Repurposing of metformin and colchicine reveals differential modulation of acute and chronic kidney injury

open access: yesScientific Reports, 2020
Acute kidney injury (AKI) is a major health problem affecting millions of patients globally. There is no effective treatment for AKI and new therapies are urgently needed.
Maryam El-Rashid   +7 more
doaj   +1 more source

Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology

open access: yesTrials, 2023
Background Patients presenting with acute interstitial nephritis (AIN) of unknown aetiology, probably the earliest presentation of chronic kidney disease of unknown aetiology (CKDu), have been treated with oral prednisolone and doxycycline by physicians ...
Zeid Badurdeen   +12 more
doaj   +1 more source

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