Results 181 to 190 of about 61,935 (262)

Population Pharmacokinetic/Pharmacodynamic Modeling of Tacrolimus in Renal Transplant Recipients: Impact of CYP3A5 Genotype and Wuzhi Capsule Co-Medication. [PDF]

Drug Des Devel Ther
Xiang Q, Yang Y, Li G, Chen S, Yang Y, Liu L, Yu X.   +6 more
europepmc   +1 more source

Pre‐Existing and New‐Onset Atrial Fibrillation in Patients Undergoing Transcatheter Aortic Valve Implantation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Atrial fibrillation (AF) is a frequent comorbidity in patients with severe aortic valve stenosis undergoing transcatheter aortic valve implantation (TAVI). In addition, new‐onset AF can occur after TAVI. However, data on how AF affects outcomes in patients undergoing TAVI remain conflicting.
Kimberley I. Hemelrijk, Astrid C. van Nieuwkerk, Philomene J. Vojacek, Livia Gheorge, Didier Tchétché, Fabio S. de Brito Jr., Marco Barbanti, Ran Kornowski, Azeem Latib, Augusto D'Onofrio, Flavio Ribichini, Geoffrey Yanes Bowden, Nicolas Dumonteil, Rogerio Sarmento Leite, Samantha Sartori, Paola D'Errigo, Giuseppe Tarantini, Stefano Andreaggi, Katia Orvin, Matteo Pagnesi, Lluis Asmarats, George Dangas, Roxana Mehran, Ronak Delewi   +23 more
wiley   +1 more source

Optimizing growth in pediatric renal transplant recipients: An update. [PDF]

World J Transplant
Gamage M, Ranawaka R.
europepmc   +1 more source

Radial Versus Femoral Access for Diagnostic Coronary Angiography: Insights From a Tertiary Academic Center in Johannesburg

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background The radial artery is the preferred access for performing diagnostic coronary angiograms (DCA). However, data on the safety and efficacy of radial compared to femoral access in low‐ and middle‐income countries is limited. Aims This study aims to evaluate the safety and efficacy of radial versus femoral access in patients referred for
Khulasande Liso Ntaka, Dineo Mpanya, Umar G Adamu, Thomas Kalk, Nqoba Tsabedze   +4 more
wiley   +1 more source

Investigating the pathways of medication adherence in renal transplant recipients based on the COM-B model: the parallel mediating effects of beliefs and emotion regulation efficacy. [PDF]

Front Pharmacol
Zhou L, Cheng K, Chen L, Han S, Wan J.
europepmc   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Surgical Site Infections After Wound Closure With Staples Versus Sutures in Post-renal Transplant Recipients: A Prospective Observational Study. [PDF]

Cureus
Ullah I, Manan F, Moosa M, Rehman KU.
europepmc   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, EarlyView.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Effectiveness of eHealth for Medication Adherence in Renal Transplant Recipients: Systematic Review and Meta-Analysis. [PDF]

J Med Internet Res
Zhou L, Cheng K, Chen L, Hou X, Wan J.
europepmc   +1 more source

Ruxolitinib Pharmacokinetics and Exposure–Toxicity Relationship in Hematologic Malignancies and Immune‐Mediated Diseases: A Prospective Observational Study

Clinical Pharmacology &Therapeutics, EarlyView.
Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet, Sara C. Meyer, Francesco Grandoni, Emmanuel Haefliger, Monika Nagy‐Hulliger, Jörg P. Halter, Jakob R. Passweg, David Haefliger, Carine Bardinet, Laurent A. Decosterd, Monia Guidi, François R. Girardin   +11 more
wiley   +1 more source