Results 181 to 190 of about 721,252 (305)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

New mouse models for exploring renal tumor extension into the inferior vena cava. [PDF]

Commun Biol
Li X, Li H, Zhao X, Wang J, Li D, Li Q, Xu Q, Wu S, Liang Q, Li S, Jiao Q, Liu K, Du S, Peng C, Wang B, Gu L, Zhang X, Huang Q, Ma X.   +18 more
europepmc   +1 more source

Dataset on renal tumor diameter assessment by multiple observers in normal-dose and low-dose CT. [PDF]

Data Brief, 2023
Borgbjerg J, Larsen NE, Salte IM, Grønli NR, Klæstrup E, Negård A.   +5 more
europepmc   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

A Benign Renal Tumor With Serious Consequences: A Case Report of Juxtaglomerular Cell Tumor and Chronic Renal Disease in a Teenager. [PDF]

Case Rep Pediatr
Courtney R, Dahlinghaus E, Omoloja A, Boyd JT, Smith M, Biederman L, Ndengabaganizi I, Robie DK, Al Dughiem A.   +8 more
europepmc   +1 more source

An etiological assessment of a deep vein thrombosis led to the discovery of a renal tumor collision: Case report. [PDF]

Int J Surg Case Rep, 2023
El Farhaoui H, Elmoudane A, Jdaini A, Moutaouakil A, Barki A.   +4 more
europepmc   +1 more source

Renal homotransplantation in man: followup of 189 cases [PDF]

, 1970
Gray, S, Matineau, GL, Starzl, TE, Takagi, H   +3 more
core  

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

Advanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo, Grant Phillips, Sriganesh Srihari, Áine Farrell, Binny Jaradi, Kira J. Fitzpatrick, John W. Yaxley, Hemamali Samaratunga, Paul N. Mainwaring, Ke‐lin Ru, Darren J. Korbie, Scott A. Tomlins, Matthew J. Roberts, Robert A. Gardiner, Matt Trau   +14 more
wiley   +1 more source

Using deep learning to differentiate among histology renal tumor types in computed tomography scans. [PDF]

BMC Med Imaging
Kan HC, Lin PH, Shao IH, Cheng SC, Fan TY, Chang YH, Huang LK, Chu YC, Yu KJ, Chuang CK, Wu CT, Pang ST, Peng SJ.   +12 more
europepmc   +1 more source