Results 51 to 60 of about 14,353 (287)

Fumarate Hydratase Lactylation Exacerbates Traumatic Brain Injury Pathology via Mitochondrial Dysfunction and Neuroinflammation

Advanced Science, EarlyView.
Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian, Shuoyao Ma, Bo Yang, Fei Gao, Hao Guo, Haixiao Liu, Xun Wu, Wenxing Cui, Jingyu Dong, Qian Lin, Yufeng Ge, Jin Ma, Jiazhen Zhao, Yongzhi Zhang, Dongzhi Xue, Jiaxin Tian, Ziwen Zhang, Kai Wang, Meng Xu, Dayun Feng, Jinpeng Zhou, Yan Qu   +21 more
wiley   +1 more source

Toponymic Environments of New Urban Settlements in Transbaikalia: Soviet Legacy and Contemporary Nomenclature

Oriental Studies
Introduction. Despite studies in Transbaikalia’s onomastics are voluminous enough, the toponymic environments of its urban settlements remain somewhat understudied. Goals.
Nikolay S. Baikalov, ulia N. Varfolomeeva2   +1 more
doaj   +1 more source

DECOMMUNIZATION OF THE NAMES OF THE SETTLEMENTS AND REGIONS IN UKRAINE: THE BASIS, THE PROCESS, AND THE RESULTS

Місто: історія, культура, суспільство, 2017
For almost eight months - from November 2015 to July 2016 - the most significant number of settlements in Ukraine since independence got new names. The names were changed following the Law of Ukraine “On Condemnation of Communist and National Socialist (
Bohdan Korolenko, Ihor Karetnikov, Maksym Maiorov   +2 more
doaj   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

COMMUNIZATION AND DE-COMMUNIZATION OF TOPONYMS IN KAMYANETS’-PODIL’S’KY

Місто: історія, культура, суспільство, 2017
The Communisation about change on toponymy map in Kamyanets’-Podil’s’ky during the 1920s – early ХХІ century. Within the first 20 years of Soviet rule, most microtoponyms that did not fit into the ideological system of the Communist Party were renamed –
Ihor Starenkyi, Yaryna Zaishliuk
doaj   +1 more source

Fast, Long-Lived Renaming Improved and Simplified

, 1996
. In the long-lived M-renaming problem, N processes repeatedly acquire and release names ranging over f0; :::; M \Gamma1g, where M ! N . It is assumed that at most k processes concurrently request or hold names.
Juan A. Garay, Mark Moir
core   +1 more source

Low‐Power Control Of Resistance Switching Transitions in First‐Order Memristors

Advanced Electronic Materials, EarlyView.
Joule losses are a serious concern in modern integrated circuit design. In this regard, minimizing the energy necessary for programming memristors should be handled with care. This manuscript presents an optimal control framework, allowing to derive energy‐efficient programming voltage protocols for resistance switching devices. Following this approach,
Valeriy A. Slipko, Alon Ascoli, Fernando Corinto, Yuriy V. Pershin   +3 more
wiley   +1 more source

Rural Labor Supply and Economic Opportunities: Commuting, Migration, Tariffs, and Immigration

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Some rural counties remain dependent on agricultural or manufacturing jobs, but an increasing proportion have diversified economics. Rural counties also differ in their abilities to commute to an urban market characterized by higher wages and labor productivity.
Peter F. Orazem, Mary C. Ahearn
wiley   +1 more source

Some Good Reasons for Renaming Places, and Some not so Good Ones: a Cross-Cultural Sketch. In Honour of Canada’s 150th Birthday and the Year of Reconciliation [PDF]

Вопросы ономастики, 2018
The note focuses on the initiative of renaming some places in Canada to celebrate the year of Canada’s 150th anniversary, as well as the Year of Reconciliation (2017). The initiative aims at revitalizing the original names given by the First Nations, i.e.
Gunter Schaarschmidt
doaj   +1 more source

khipulab/renaming

<p>The code in this repository can be used to reproduce the renaming procedure described in <a href="https://doi.org/10.1017/laq.2023.71">Brezine, Clindaniel, Ghezzi, Hyland and Medrano (2024)</a> "A New Naming Convention for ...
OKR Team
core   +1 more source