Results 101 to 110 of about 539,429 (296)
El artículo cuestiona el aparente desequilibrio entre los fines perseguidos y los medios empleados en el dibujo practicado en las escuelas y estudios de arquitectura. Los dibujos pretendidamente realistas de la producción gráfica actual no es la única aplicación de los programas informáticos, ni la más valiosa.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Depth-Supervised and Curvature-Optimized 3D Gaussian Splatting for Scene Reconstruction
Recently, 3DGS has achieved revolutionary advancements in dynamic rendering and novel view synthesis tasks. The Adaptive Density Control (ADC) algorithm plays a pivotal role in 3DGS, utilizing an image gradient-based average gradient threshold to ...
Antong Li, Lutao Wang, Ziwei Wang
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Today the algorithmic moves off the white- board and into the world, producing subjectivities, articulating relationships, and shaping behaviours. Yet to obtain its objectives, the algorithmic must draw upon bodies, flows, and materials — matter which is contentious and agents which have their own intentionalities.
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
From Rendering to Semantization: Intensified Architectural Semantics with Generative AI
Generative AI is often framed in architecture as a faster rendering engine, able to turn sketches, models, and prompts into persuasive images. uch a view collapses two distinct operations: rendering and semantization.
Cintya Eva Sanchez Morales +1 more
doaj
Identification of animal species in rendering products by dna technology [PDF]
After bovine spongiform encephalopathy (BSE) outbreak, the use of especially ruminant byproducts in animal rations is under strict control. An animal feedstuff sample was sent from the Turkish Republic, Mersin Customs Directorate in order to identify the
Ercan Kurar +4 more
doaj

