Results 61 to 70 of about 3,300 (212)

Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia. [PDF]

, 2003
BACKGROUND\ud \ud Mutations of the transforming growth factor beta (TGFbeta) receptor components ENDOGLIN and ALK-1 cause the autosomal dominant vascular disorder hereditary haemorrhagic telangiectasia (HHT).
Abdalla, S A, Elliott, C G, Flanagan, J A, Gruenig, E, Halme, M, Harrison, R E, Kermeen, F, Laitinen, T, Machado, R D, McLaughlin, V, Morrell, N W, Olschewski, H, Robbins, I M, Rowell, J, Räisänen-Sokolowski, A, Sankelo, M, Trembath, R C   +16 more
core   +2 more sources

Complications and mortality in hereditary hemorrhagic telangiectasia: a population-based study [PDF]

, 2015
OBJECTIVES: Studies report that the risks of significant neurologic complications (including stroke, cerebral abscess, and migraine) and hemorrhagic sequelae are high in patients with hereditary hemorrhagic telangiectasia (HHT), and that life ...
Donaldson, J.W., Fogarty, Andrew W., Hall, Ian P., Hubbard, R.B., McKeever, Tricia M.   +4 more
core   +1 more source

Hematochezia: An abnormal presenting symptom of an extensive vascular malformation in a 6‐year‐old boy

JPGN Reports, Volume 6, Issue 3, Page 300-304, August 2025.
Abstract Gastrointestinal (GI) bleeding can be a common symptom in the pediatric population. Vascular malformations, which cause symptoms based on their location and effect on surrounding structures, are an uncommon cause of GI bleeding. We present the case of a 6‐year‐old male with a 1‐year history of hematochezia, constipation, and microcytic anemia.
Kathleen Ordas, Joy Brusenback, Sahana Ummadi, Shannon Tocchio, Razan Alkhouri, Soha Shah   +5 more
wiley   +1 more source

Infective endocarditis with Osler’s nodule in a patient with Osler’s disease: a case report and review of the literature

Journal of Medical Case Reports, 2022
Background Hereditary hemorrhagic telangiectasia, also known as Osler–Weber–Rendu disease, induces arteriovenous malformations in visceral organs. Arteriovenous malformations increase the risk of severe infections and are a common complication associated
Genki Naruse, Takatomo Watanabe, Hiroyuki Okura   +2 more
doaj   +1 more source

Can iron treatments aggravate epistaxis in some patients with hereditary hemorrhagic telangiectasia?

, 2016
Objectives/Hypothesis To examine whether there is a rationale for iron treatments precipitating nosebleeds (epistaxis) in a subgroup of patients with hereditary hemorrhagic telangiectasia (HHT).
Anand, Braverman, Breuer, Brinkerhoff, Buscarini, Campenhout, Chan, Devlin, Dresow, Elphick, Fairbanks, Finnamore, Finnamore, Folz, Gaillard, Ganz, Geirdal, Geisthoff, Hallberg, Harvey, Hebert, Hoag, Hosman, Hunter, Hutchinson, Ingrand, Karnezis, Kartikasari, Kautz, Lin, Livesey, Loaec, Lopez, Lund, Mahoney, McDonald, McLean, Mehta, Merlo, Mollet, Nelson, Patel, Pittman, Porter, Richer, Rimmer, Rowand, Santhirapala, Scheiber-Mojdehkar, Schmidt, Schumann, Shander, Shovlin, Shovlin, Shovlin, Shovlin, Silva, Tan, Thane, Woods, Yaniv, Yin   +61 more
core   +1 more source

Optimal management of hereditary hemorrhagic telangiectasia [PDF]

, 2014
Hereditary hemorrhagic telangiectasia (HHT), also known by the eponym Osler–Weber–Rendu syndrome, is a group of related disorders inherited in an autosomal dominant fashion and characterized by the development of arteriovenous malformations (AVM) in the ...
Garg, Neetika, Gupta, Arjun, Khunger, Monica, Kumar, Nilay   +3 more
core   +1 more source

Variant distribution and characterization of hereditary hemorrhagic telangiectasia in Chinese patients

Eye &ENT Research, Volume 2, Issue 1, Page 53-61, March 2025.
Abstract Background Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder with variable manifestations, including recurrent epistaxis, telangiectasias, arteriovenous malformations, and family history. It is caused by heterozygous null alleles of ENG, ACVRL1, SMAD4, or BMP9, with delayed clinical diagnosis.
Yali Zhao, Xiangdong Wang, Yuhui Ouyang, Lin Xi, Yuan Zhang, Yan Zhao   +5 more
wiley   +1 more source

Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee

Journal of Pediatric Gastroenterology and Nutrition, Volume 80, Issue 3, Page 510-532, March 2025.
Approach to Anaemia in paediatric Gastrointestinal Disease Abstract Anaemia is a frequent consequence of many gastrointestinal (GI) diseases in children and it can even be the initial presenting symptom of underlying chronic GI disease. The definition of anaemia is age and gender‐dependent and it can be classified based on pathophysiology, red cell ...
Ilse Julia Broekaert, Amit Assa, Osvaldo Borrelli, Marco Deganello Saccomani, Matjaž Homan, Javier Martin‐de‐Carpi, Emmanuel Mas, Erasmo Miele, Zrinjka Misak, Sara Sila, Mike Thomson, Christos Tzivinikos, Jernej Dolinsek   +12 more
wiley   +1 more source

Síndrome de Rendú-Osler-Weber con compromiso gastrointestinal, hepático y pancreático

Revista Colombiana de Gastroenterología
El síndrome de Rendu-Osler-Weber (SROW) se caracteriza por el desarrollo de estructuras vasculares aberrantes, tales como microvasos dilatados y malformaciones arteriovenosas (MAV) en la piel, el tracto gastrointestinal (GI), los pulmones, el hígado, el
Diego Armando Huanay-Martínez, Siomara Aransuzú Chávez Sánchez, Álvaro Bellido-Caparó   +2 more
doaj   +1 more source

Portal Hypertension—Noninvasive Multiparametric Ultrasound‐Based Criteria and Measurements

Portal Hypertension &Cirrhosis, Volume 4, Issue 1, Page 44-65, March 2025.
The review article discusses B‐mode ultrasound (US), color Doppler imaging, arterial Doppler indices, contrast‐enhanced ultrasound (CEUS), endoscopic ultrasound (EUS) and elastography methods in the diagnosis, grading and staging of portal hypertension.
Kathleen Möller, Riyad Abu El Hija, Xiaolong Qi, Christian Jenssen, Sven Mutze, Burkhard Möller, Benjamin Misselwitz, Christoph F. Dietrich   +7 more
wiley   +1 more source