Results 61 to 70 of about 200,809 (269)

Spatial Analysis and Social Network Analysis for Structural Restoration of Settlements: A Case Study of the Great Wall Under the Influence of a Non-Agricultural Civilization

Buildings
The settlements of the Great Wall are the product of the overlap of ancient Chinese agricultural civilization and non-agricultural civilization. The structure of the settlement system is of great value for understanding the law of defense engineering and
Dan Xie, Jinbiao Du, Meng Wang
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Less Talk, More Builds: The Mixed-Income Residential Tower Model of the University of Winnipeg Community Renewal Corporation

Engaged Scholar Journal
The search for and replication of scalable models for affordable housing amid North America’s housing insecurity crisis has been frustratingly slow. Governments are flailing—and, so far, failing—as they try to put in place the necessary policies and ...
Edward T. Jackson, Jeremy Read
doaj   +1 more source

Data-driven support for smart renewal of urban neighbourhoods

Smart Cities and Regional Development Journal, 2018
The paper provide an insight into the research conducted by the Faculty of Architecture (University of Ljubljana), and the Urban institute of Slovenia committed to the assessment of the efficiency related to the management of local resources at the ...
Spela VEROVSEK, Matevz JUVANCIC, Tadeja ZUPANCIC   +2 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Integrating Machine Learning in Geotechnical Engineering: A Novel Approach for Railway Track Layer Design Based on Cone Penetration Test Data

Infrastructures
The cone penetration test (CPT) has emerged as a cost-effective and time-efficient method for assessing soil conditions relevant to railway track infrastructure.
Matthieu Bernard
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Toward Appropriate Missiology for Post-Soviet Evangelicals: Global Missiological Trends and Local Realities

Богословські роздуми: Східноєвропейський журнал богословʼя, 2011
The future of missions in post-Soviet countries is tied to the formation/development of an appropriate, indigenous, authentic, effective, comprehensive missiological paradigm, which is based on Biblical principles, opens up into a holistic theoretical ...
Michael CHERENKOV
doaj  

Comprehensive Review of Ecosystem Services of Community Gardens in English- and Chinese-Language Literature

Buildings
Community gardens are regarded as important green spaces that promote sustainable cities. Some studies have explored the ecosystem services of community gardens in different areas.
Xiaoying Ding, Haotian Zhang, Xiaoxiao Fan, Xiaoyu Zhang, Xiaopeng Yue, Ping Shu   +5 more
doaj   +1 more source