Results 71 to 80 of about 130,944 (260)
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Superposed continuous renewal processes A Markov renewal approach
Let \((S_n)_{n \geq 1}\) be the point process obtained as superposition of \(p \geq 2\) independent renewal processes. Though in general this process is no longer a renewal process, it shares the asymptotic properties of renewal processes as given in the renewal theorems. This has been shown by \textit{C. Y. T. Lam} and \textit{J. P.
openaire +2 more sources
Error statistics for concatenated systems on non-renewal time-varying channels
The statistics of the error process generated by a discrete super channel formed by the concatenation of a constrained encoder, a non-renewal finite state channel (FSC), and a constrained decoder is studied in this paper.
Cecilio Pimentel
doaj +1 more source
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao +6 more
wiley +1 more source
Updated peer review concerning the risk to mammals and bees for the active substance indoxacarb
Following the completion of the pesticides peer review process in the context of the renewal of the approval of indoxacarb in accordance with Commission Implementing Regulation (EU) No 844/2012, EFSA identified critical areas of concern in the area of ...
European Food Safety Authority (EFSA)
doaj +1 more source
Web renewal counting processes and their applications in insurance
This paper investigates a nonstandard renewal counting process with dependent inter-arrival times-web renewal process. Several limit properties, including the tail of the exponential moment which is a crucial condition in many situations, are obtained ...
Rong Li, Xiuchun Bi, Shuguang Zhang
doaj +1 more source
Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
Objective This study aims to develop hip morphology‐based radiographic hip osteoarthritis (RHOA) risk prediction models and investigates the added predictive value of hip morphology measurements and the generalizability to different populations. Methods We combined data from nine prospective cohort studies participating in the Worldwide Collaboration ...
Myrthe A. van den Berg +26 more
wiley +1 more source

