Results 41 to 50 of about 18,904 (219)

α-Lipoic Acid Reduces Hypertension and Increases Baroreflex Sensitivity in Renovascular Hypertensive Rats

open access: yesMolecules, 2012
Renovascular hypertension has robust effects on control of blood pressure, including an impairment in baroreflex mechanisms, which involves oxidative stress.
Valdir A. Braga   +3 more
doaj   +1 more source

Should an Accessory Renal Artery be Considered as a Cause of Hypertension in Adolescents: a Case Report

open access: yesActa Clinica Croatica, 2023
The role of an accessory renal artery in the pathogenesis of hypertension is still controversial. In this report, we describe a previously healthy 16-year-old girl with an accessory right renal artery who presented with hypertensive urgency (no ...
Bernardica Valent Morić   +2 more
doaj   +1 more source

The Role of Natriuretic peptides in Renovascular Hypertension and its correlation with the Evolution of Myocardial Hypertrophy [PDF]

open access: yes, 2010
The interactions between pressure and volume overload that occur in hypertension lead to different patterns of cardiac hypertrophy and to increase in natriuretic peptides (NPs).
Cavallero, Carmen Susana   +4 more
core  

The insulin‐like growth factor system and the progression of renal complications of type 2 diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Chronic kidney disease is associated with dysregulation of the insulin‐like growth factor (IGF) system. Alterations in IGF bioavailability, driven by IGF binding proteins (IGFBPs), may influence the decline in renal function. However, the longitudinal relationship between baseline IGF‐I, IGF‐II, IGFBPs and progression of kidney ...
Adrian Heald   +13 more
wiley   +1 more source

A Newly Isolated Carboxymethyl-Glucan (CM-G) Restores Depressed Baroreflex Sensitivity in Renovascular Hypertensive Rats

open access: yesFrontiers in Physiology, 2018
This study was designed to investigate the effects of a newly synthesized carboxymethyl-glucan (CM-G) on blood pressure (BP), baroreflex sensitivity (BRS) and sympathetic vascular modulation in renovascular hypertensive rats.
Alynne Carvalho-Galvão   +7 more
doaj   +1 more source

Paraventricular Nucleus Infusion of Oligomeric Proantho Cyanidins Improves Renovascular Hypertension

open access: yesFrontiers in Neuroscience, 2021
Oxidative stress plays an important role in the pathogenesis of hypertension. Oligomeric proantho cyanidins (OPC) is the main polyphenol presents in grape seed and is known for its potent antioxidant and anti-inflammatory properties. In the present study,
Xiao-Jing Yu   +11 more
doaj   +1 more source

The autonomic nervous system and renal physiology [PDF]

open access: yes, 2014
Research in resistant hypertension has again focused on autonomic nervous system denervation – 50 years after it had been stopped due to postural hypotension and availability of newer drugs.
D’Elia, John A, Weinrauch, Larry A
core   +1 more source

Kinetic and structural characterisation of domain‐specific angiotensin I‐converting enzyme inhibition by captopril, rentiapril and zofenoprilat

open access: yesThe FEBS Journal, EarlyView.
Angiotensin I‐converting enzyme (ACE) contains two catalytic domains (nACE and cACE) and is a key therapeutic target for hypertension and cardiovascular disease. Current ACE inhibitors (ACEi) nonselectively inhibit both domains, causing adverse effects. Selective inhibition requires an understanding of domain‐specific binding.
Kyle S. Gregory   +3 more
wiley   +1 more source

Angiotensin II and angiotensin-(1-7) in paraventricular nucleus modulate cardiac sympathetic afferent reflex in renovascular hypertensive rats. [PDF]

open access: yesPLoS ONE, 2012
The enhanced cardiac sympathetic afferent reflex (CSAR) is involved in the sympathetic activation that contributes to the pathogenesis and progression of hypertension. Activation of AT(1) receptors by angiotension (Ang) II in the paraventricular nucleus (
Hai-Jian Sun   +4 more
doaj   +1 more source

Statin Therapy Protects White Matter in Cerebral Small Vessel Disease Independent of Lipid‐Lowering: Biomarker and Neuroimaging Evidence

open access: yesBrain and Behavior, Volume 16, Issue 5, May 2026.
This study, through an analysis of neuroimaging markers, biomarkers of white matter damage, and the volume of the hippocampal fimbria (a white matter structure) in patients with cerebral small vessel disease (CSVD), revealed that the protective effect of statin therapy against white matter damage in CSVD patients is independent of its lipid‐lowering ...
Rui Wang   +5 more
wiley   +1 more source

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