Results 31 to 40 of about 112,779 (281)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Probation, rehabilitation and reparation [PDF]

open access: yes, 2009
This paper is a version of the 2nd Annual Martin Tansey Memorial Lecture, organised by the Association for Crime and Justice Research and delivered on 7th May 2009 at the headquarters of the Probation Service of Ireland in Dublin.
McNeill, Fergus
core  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Acknowledging ecological debt: towards just, humane and sustainable food systems in Africa

open access: yesFrontiers in Animal Science
This review interrogates the historical and ongoing consequences of the Global North’s industrialization trajectory on the Global South, including the industrial agriculture systems subsequently exported to the Global South.
Mwenda Mbaka, Janice H. Cox
doaj   +1 more source

Restorative justice, mediation and relational conflict resolution in work with young people in residential care [PDF]

open access: yes, 2009
Original article can be found at: http://www.informaworld.com/smpp/title~content=t713665951~db=all Copyright Informa / Taylor and FrancisConflict resolution approaches such as restorative justice and mediation are becoming increasingly important in ...
Littlechild, B.
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Compensatory and Alimentary Obligations in Civil Responsibility [PDF]

open access: yesمطالعات فقه و حقوق اسلامی, 2017
The obligation to compensate damage, as the main goal of civil responsibility, is an evident and global necessity. Nowadays, the extension of concept of damage and review of basis of obligation had led to the development of civil responsibility. However,
ali ghesmati
doaj   +1 more source

Hacia un horizonte alternativo para la reparación en salud en Chile: Reflexiones desde la práctica tras 50 años de impunidad

open access: yesConfluenze, 2023
This paper reflects on health reparation practices in the context of neoliberal hegemony and long-lasting impunity. It builds on an ethnographical approach (2019-2022) to four health reparation initiatives created by users and workers of a state ...
Natalia Picaroni Sobrado
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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