Results 81 to 90 of about 112,779 (281)
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Problems of Cost Evaluation of Damage to Environmental Objects
Теория и практика судебной экспертизы, 2019 The article discusses the key issues of cost evaluation of damage to the environment. This is a problem of legislative regulation arising from the lack of clear criteria of harm materiality to environmental objects; the problem of regulation of the ...
G. G. Omel’yanyuk +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Вестник хирургии имени И.И. Грекова, 2018 The authors analyzed clinical (size, tissue oxygenation), histological (light microscopy) and immunohistochemical (CD68, MMP-9, TIMP-1) features of reparative processes of soft tissue of lower extremities in patients with diabetes mellitus against the ...
E. L. Zaitseva +5 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
PatologìâToday, diabetes mellitus (DM) represents a problem on which the attention of endocrinologists, general practitioners, and dentists is focused. Early pathological changes, which manifest themselves in the oral cavity, determine the relevance and social ...
A. V. Abramov, K. S. Hanchev
doaj +1 more source
, 2007 Reparations for victims of gross human rights violations are becoming an increasingly acknowledged feature in post-authoritarian and post-conflict societies coping with the legacy of a violent past.
Greiff, Pablo de, Rubio-Marín, Ruth
core
An Interplay of Learning, Creativity and Narrative Biography in a Mental Health Setting: Bertie's Story [PDF]
, 2007 This paper describes selected findings from a research study exploring the use of a basic literacy/creative writing course provided in a community setting for adults with long-term mental health difficulties.
Sagan, Olivia
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
S’accorder en Terre Ferme vénitienne (Castelgomberto, province de Vicence, 1595-1598)
CriminocorpusFor a long time, historians of law and justice have paid attention above all to the crimes committed and the judgments pronounced, and neglected the regular work accomplished by notaries, which they exercise in cities or the countryside.
Lucien Faggion
doaj +1 more source