Results 71 to 80 of about 176,302 (282)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Evidence of epistatic suppression of repeat fruiting in cultivated strawberry

BMC Plant Biology, 2019
Background Consumers purchase fresh strawberries all year long. Extending the fruiting season for new strawberry cultivars is a common breeding goal. Understanding the inheritance of repeat fruiting is key to improving breeding efficiency.
K. S. Lewers, P. Castro, J. F. Hancock, C. K. Weebadde, J. V. Die, L. J. Rowland   +5 more
doaj   +1 more source

Influence of controlled breeding techniques on fertility and plasma progesterone, protein and cholesterol profile in true anestrus and repeat breeding buffaloes [PDF]

Veterinary World, 2014
Aim: The aim was to evaluate the estrus response, conception rate and plasma profile of progesterone, protein and cholesterol following use of different hormonal protocols in anestrus and repeat breeding buffaloes.
K. K. Savalia, A. J. Dhami, K. K. Hadiya, K. R. Patel , N. P. Sarvaiya   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Estrus quality, non-return rate and conception rate in the incidence of repeat breeding in dairy cow after 2%povidone iodine therapy combined with prostaglandin F2α at KUD Tani Wilis Tulungagung

Ovozoa: Journal of Animal Reproduction
Repeat breeding is a condition in which cows fail to conceive after being bred three or more times. This study aims to determine the quality of estrus, non-return rate (NRR) and conception rates obtained after cows were treated with 2% povidone iodine ...
Amira Halimah Zahrorona, Sri Pantja Madyawati, Pudji Srianto, Hermin Ratnani, Sunaryo Hadi Warsito, Sri Hidanah   +5 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Prevalence, risk factors and constraints in control of repeat breeding in dairy animals of Punjab

Indian Journal of Animal Sciences, 2019
The present study investigated the occurrence of repeat breeding (RB) and constraints in controlling this disease in cattle and buffalo in Punjab. Livestock owners/households (720) constituted the ultimate sampling units for the study.
M H MALIK, H K VERMA, R K SHARMA
doaj   +1 more source

Advances in Plant-Nematode Interactions with Emphasis on the Notorious Nematode Genus Meloidogyne. [PDF]

, 2019
Plant infections by plant-parasitic nematodes (PPNs) continue to be one of the major limitations in agricultural systems. Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are one of the most important groups of PPNs worldwide.
Kaloshian, Isgouhi, Teixeira, Marcella
core  

Influence of spatial and temporal dynamics of agricultural practices on the lesser kestrel [PDF]

, 2011
1. European agriculture is facing dramatic changes that are likely to have marked impacts on farmland biodiversity. There is an urgent need to develop land management strategies compatible with the conservation of biodiversity.2.
Amano, Blake, Bustamante, Butler, Catry, Catry, Catry, Chamberlain, Cordeiro, Donald, Donázar, Dunning, ESRI, Fenner, Franco, Franco, Herbers, Johst, Kleijn, Lepley, Masman, Ostermann, Peet, Perkins, Pettifor, R Development Core Team, Ricklefs, Robson, Rodríguez, Rodríguez, Rodríguez, Siriwardena, Stephens, Stephens, Sutherland, Sutherland, Suárez, Tella, Tilman, van Wingerden, Whittingham, Wolff, Wretenberg   +42 more
core   +1 more source