Results 11 to 20 of about 264,015 (173)

Repeat hepatectomy is independently associated with favorable long‐term outcome in patients with colorectal liver metastases

Cancer Medicine, 2017
Up to three‐quarters of patients undergoing liver resection for colorectal liver metastases (CRLM) develop intrahepatic recurrence. Repeat hepatic resection appears to provide the optimal chance of cure for these patients.
Christopher P. Neal, Gael R. Nana, Michael Jones, Vaux Cairns, Wee Ngu, John Isherwood, Ashley R. Dennison, Giuseppe Garcea   +7 more
doaj   +5 more sources

Repeat hepatectomy for recurrent hepatocellular carcinoma: a local experience and a systematic review [PDF]

World Journal of Surgical Oncology, 2010
Background This study aimed to assess the efficacy and safety of repeat hepatectomy for recurrent hepatocellular carcinoma (HCC). Methods Thirty-seven patients who underwent a curative repeat hepatectomy in our hospital were retrospectively studied.
Tan Yunchang, Yin Zhengfeng, Li Bin, Sui Chengjun, Zhou Yanming, Yang Jiamei, Liu Zhenyu   +6 more
doaj   +2 more sources

Repeat hepatectomy with systemic chemotherapy might improve survival of recurrent liver metastasis from colorectal cancer—a retrospective observational study

World Journal of Surgical Oncology, 2019
Background Although hepatectomy for metastatic colorectal cancer (mCRC) prolongs survival in up to 40% of people, recurrence rates approach 70%. We used a multidisciplinary approach to treat recurrent liver metastases, including chemotherapy, surgery ...
Hiroshi Matsuoka, Zenichi Morise, Chihiro Tanaka, Takahiro Hayashi, Yoshiaki Ikeda, Koutarou Maeda, Koji Masumori, Yoshikazu Koide, Hidetoshi Katsuno, Yoshinao Tanahashi, Sanae Nakajima, Tsunekazu Hanai, Yutaro Kato, Atsushi Sugioka, Ichiro Uyama   +14 more
doaj   +2 more sources

Robotic left hepatectomy with revision of hepaticojejunostomy

Asian Journal of Surgery, 2014
Laparoscopic hepatectomy and hepaticojejunostomy remain a surgical challenge despite the recent advances in minimally invasive surgery. A robotic surgical system has been developed to overcome the inherent limitations of the traditional laparoscopic ...
Kuo-Hsin Chen, Shian-Dian Chen, Ying-Da Chen, Yin-Jen Chang, Tzu-Chao Lin, Tiing-Foong Siow, U-Chon Chio, Shu-Yi Huang, Jiann-Ming Wu, Kuo-Shyang Jeng   +9 more
doaj   +2 more sources

Essential updates 2022/2023: A review of current topics in robotic hepatectomy

Annals of Gastroenterological Surgery
The liver requires careful handling intra‐operatively owing to its vital functions and complexity. Traditional open hepatectomy, while standard, is invasive and requires long recovery periods.
Tomohiko Adachi, Takanobu Hara, Hajime Matsushima, Akihiko Soyama, Susumu Eguchi   +4 more
doaj   +2 more sources

Repeat procedures for recurrent colorectal liver metastases: analysis of long-term liver regeneration and outcome

Cancer Management and Research, 2019
Valentinus T Valdimarsson,1 Katarina Hellberg,2 Torkel B Brismar,3 Ernesto Sparrelid,2 Christian Sturesson1,21Department of Clinical Sciences Lund, Surgery, Lund University, Skane University Hospital, Lund, Sweden; 2Division of Surgery, Department of ...
Valdimarsson VT, Hellberg K, Brismar TB, Sparrelid E, Sturesson C   +4 more
doaj   +1 more source

The Surgical Benefits of Repeat Hepatectomy for Colorectal Liver Metastasis [PDF]

, 2020
The most common site of distant metastasis from colorectal cancer is the liver, and hepatectomy presents the best curative treatment for recurrence of colorectal liver metastasis （CRLM）. This study aimed to identify factors of prognostic value for repeat
FUJIMORI, Akira, MURAKAMI, Masahiko, HAKOZAKI, Tomoki, YAMAZAKI, Tatsuya, KOIKE, Reiko, YAMADA, Kousuke, KUSANO, Tomokazu, WADA, Yuusuke, SHIBATA, Hideki, NOGAKI, Kouji, HIRAI, Takashi, AOKI, Takeshi, ENAMI, Yuta, KOIZUMI, Tomotake, TASHIRO, Yoshihiko, MITAMURA, Keitaro, TOMIOKA, Koudai, MATSUDA, Kazuhiro   +17 more
core   +2 more sources

Outcomes after repeat hepatectomy for colorectal liver metastases from the colorectal liver operative metastasis international collaborative (COLOMIC) [PDF]

, 2022
BackgroundResection of colorectal liver metastasis (CLM) is beneficial when feasible. However, the benefit of second hepatectomy for hepatic recurrence in CLM remains unclear.MethodsThe Colorectal Liver Operative Metastasis International Collaborative ...
Zarandi, Nima Pourhabibi, Kathleen C. Perry, Charles Cha, Carlos U. Corvera, Gawdi, Rohin, Nima Pourhabibi Zarandi, Rohin Gawdi, Perry, Kathleen C, Dourado, Justin, John A. Stauffer, Cha, Charles, Moaven, Omeed, Gregory Russell, Perry Shen, Wisneski, Andrew D, Russell, Gregory, Justin Dourado, Del Piccolo, Nico R, Tan To Cheung, Stauffer, John A, Cheung, Tan To, Corvera, Carlos U, Pourhabibi Zarandi, Nima, Omeed Moaven, Shen, Perry, Cristian D. Valenzuela, Andrew D. Wisneski, Nico R. Del Piccolo, Valenzuela, Cristian D   +28 more
core   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source