Results 151 to 160 of about 415,868 (306)

How processing choices effect repeatability in BOLD-CVR imaging. [PDF]

J Cereb Blood Flow Metab
Magnusson G, Bhogal AA, Georgiopoulos C, Cedersund G, Tobieson L, Engström M, Tisell A.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

³¹P-MRS of the Human Heart at 7 T With an Integrated Whole-Body ³¹P Radiofrequency Transmit Coil. [PDF]

NMR Biomed
Gosselink MWJM, Froeling M, Verkerk K, Klomp DWJ, Bakermans AJ, Prompers JJ.   +5 more
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Segmentation influence on the generalizability of the overall survival models in CT-based oropharyngeal carcinoma patients. [PDF]

Precis Radiat Oncol
Wang Y, Xiao X, Zhang J, Teng X, Li B, Liu K, Cai J, Ge H.   +7 more
europepmc   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Repeatability of Semi-Quantitative and Volumetric Features from Artificial-Intelligence-Guided Lesion Segmentation on ¹⁸F-DCFPyL PSMA-PET/CT Images: Results from a Test-Retest Cohort. [PDF]

Tomography
Islam MZ, Perk TG, Weisman A, Markowski MC, Pienta KJ, Whang YE, Milowsky MI, Pomper MG, Wisniewski N, Bundschuh RA, Werner RA, Gorin MA, Rowe SP.   +12 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Comparison of Reproducibility and Repeatability of Corneal Topography Measured by ATLAS 500 and ATLAS 9000 in Average Patient Population. [PDF]

Clin Ophthalmol
Tañá-Rivero P, Orts-Vila P, Tañá-Sanz P, Tañá-Sanz S, Ramos M, Tello-Elordi C.   +5 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source