Results 221 to 230 of about 4,653,774 (301)

Dose-related effects of acute cycling on executive function in children with autism spectrum disorder: a within-subject repeated-measures study. [PDF]

Front Psychol
Shi Y, Gao F, Liu Z, Cai K, Sun Z, Xu Y, Zou L, Chen A.   +7 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Hamstring-to-quadriceps ratio across menstrual cycle phases in physically active women: a repeated-measures study. [PDF]

Eur J Appl Physiol
Heinrich C, Hofstaetter H, Puschkasch-Möck S, Behringer M.   +3 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Repeated measures of mercury concentrations demonstrate persistent territory-level contamination and stable individual differences in exposure in a riverine bird predator

Ohse M, Hinninger L, Norton G, Doligez B, Bize P.   +4 more
europepmc   +1 more source

Acceleration and deceleration responses to different small-sided game formats in elite youth soccer players: a repeated-measures GPS study. [PDF]

Front Physiol
Baydemir B, Eniseler N, Kaçay Z, Talaghir LG, Manolache GM, Berdila A.   +5 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Characterizing Biomarkers of Muscle Damage in Collegiate Football Players: A Prospective, Repeated Measures Study. [PDF]

J Clin Med
Brandhurst G, Piedy E, Etheredge S, Martone M, Quiriarte HD, Phillips P, Calvert D, Lemoine NP, Marucci J, Irving BA, Zura R, Spielmann G, Johannsen NM, Matthews R.   +13 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Acute weight cycling and hydration status in elite kickboxers: a repeated-measures field study. [PDF]

BMC Sports Sci Med Rehabil
Ceylan B, Taşkın HB, Sarıkaya U, Pekel HA, Sabırlı TN.   +4 more
europepmc   +1 more source