Results 71 to 80 of about 2,746,581 (301)

Repeated stressors in adulthood increase the rate of biological ageing [PDF]

open access: yes, 2015
Background Individuals of the same age can differ substantially in the degree to which they have accumulated tissue damage, akin to bodily wear and tear, from past experiences.
Adelman, James S.   +8 more
core   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Linear Models for Multivariate Repeated Measures Data [PDF]

open access: yes
We study the general linear model (GLM) with doubly exchangeable distributed error for m observed random variables. The doubly exchangeable linear model (DEGLM) arises when the m¡dimensional error vectors are \doubly exchangeable" (de¯ned later), jointly
Anuradha Roy
core  

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Selected aspects of statistical analyses in sport with the use of STATISTICA software

open access: yesCentral European Journal of Sport Sciences and Medicine, 2013
Statistical analysis is a crucial step in all experimental studies, including sport sciences, because inappropriate analysis can lead to erroneous assumptions of performed experiments.
Nijole Jascaniene   +3 more
doaj  

Narrative exposure therapy for posttraumatic stress disorder associated with repeated interpersonal trauma in patients with severe mental illness: a mixed methods design

open access: yesEuropean Journal of Psychotraumatology, 2016
Background: In the Netherlands, most patients with severe mental illness (SMI) receive flexible assertive community treatment (FACT) provided by multidisciplinary community mental health teams.
Maria W. Mauritz   +5 more
doaj   +1 more source

Multivariate Covariance Generalized Linear Models

open access: yes, 2015
We propose a general framework for non-normal multivariate data analysis called multivariate covariance generalized linear models (McGLMs), designed to handle multivariate response variables, along with a wide range of temporal and spatial correlation ...
Bonat, Wagner Hugo, Jørgensen, Bent
core   +1 more source

Application of a New Procedure for Power Analysis and Comparison of the Adjusted Univariate and Multivariate Tests in Repeated Measures Designs [PDF]

open access: yes, 2007
A relationship between the multivariate and univariate noncentrality parameters in repeated measures designs was developed for the purpose of assessing the relative power of the univariate and multivariate approaches. An application is provided examining
Betz, M. Austin   +3 more
core   +2 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

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