Results 71 to 80 of about 1,867,213 (332)

Reducing Sexual Risk with Practice of Periodic Secondary Abstinence [PDF]

open access: yes, 2008
Objective: Test a novel intervention to help sexually experienced girls increase abstinence behaviors and attitudes. Design: A quasi-experimental repeated measures design using qualitative and quantitative data.
Haglund, Kristin
core   +1 more source

Newly diagnosed heart failure: change in quality of life, mood, and illness beliefs in the first 6 months after diagnosis [PDF]

open access: yes, 2012
Objectives. This study sought to examine how patients’ mood and quality of life (QoL) change during the early high-risk period after a diagnosis of heart failure (HF) and to identify factors that may influence change. Design.
Astin   +34 more
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Associations of objective and subjective neighborhood measures with cognitive change in a repeated measurement burst design [PDF]

open access: bronze, 2023
Jinshil Hyun   +6 more
openalex   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Hysteroscopy in women with implantation failures after in vitro fertilization: Findings and effect on subsequent pregnancy rates

open access: yesMiddle East Fertility Society Journal, 2010
Objective: To evaluate the effect of hysteroscopic endometrial cavity evaluation and management prior to IVF in patients with repeated implantation failures. Design: Retrospective cohort study. Setting: Private assisted reproduction unit.
Fatma Aletebi
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Evaluation of Die Trim Morphology Made by CAD-CAM Technology [PDF]

open access: yes, 2017
Statement of problem The die contour can affect the emergence profile of prosthetic restorations. However, little information is available regarding the congruency between a stereolithographic (SLA) die and its corresponding natural tooth.
Agrawal, Pratiksha   +3 more
core   +1 more source

Social desirability and self-reported driving behaviours: Should we be worried? [PDF]

open access: yes, 2010
Original article can be found at: http://www.sciencedirect.com/science/journal/13698478 Copyright Elsevier Ltd.There is widespread use of self-report measures of driving behaviour in the traffic psychology literature, despite the frequent criticism that ...
Sullman, M.J.M., Taylor, J.E.
core   +1 more source

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