Results 171 to 180 of about 90,856 (330)

Bacterioplankton Communities in Dissolved Organic Carbon-Rich Amazonian Black Water. [PDF]

open access: yesMicrobiol Spectr, 2023
Sylvain FÉ   +6 more
europepmc   +1 more source

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

open access: yesAdvanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong   +13 more
wiley   +1 more source

Treatment of Tinea cruris with individualized Homoeopathic medicine by using Synthesis repertory: A case study [PDF]

open access: diamond, 2023
Ashish J Kareliya   +4 more
openalex   +1 more source

Mozart and l'impresario

open access: yes, 2006
In May 1856, less than a year after opening, Jacques Offenbach’s Théâtre des Bouffes-Parisiens mounted a production of Mozart’s Der Schauspieldirektor entitled L’Impresario.
Everist, Mark
core  

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

ARTHUR SCHOPENHAUER'S QUEST OF MUSICAL REPERTORY, ARHYTHMIA AND WILLINGNESS

open access: diamond, 2023
Wika Dwi Darma   +4 more
openalex   +2 more sources

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

open access: yesAdvanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang   +10 more
wiley   +1 more source

REPERTORY AND ROLE OF THE PRECEDENT PHENOMENA IN DIFFERENT AGE GROUPS

open access: bronze, 2017
O Nosaeva   +24 more
openalex   +1 more source

Home - About - Disclaimer - Privacy