Results 71 to 80 of about 24,142 (282)
Prairie Repertory Theatre 1977 Season
, 1977 Program and photograph from the 1977 Prairie Repertory Theatre season. Plays were You're a Good Man Charlie Brown, The Miracle Worker, No Sex Please, We're British, and Fiddler on the ...
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Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Prairie Repertory Theatre 1972 Season
, 1972 Posters, programs, and photographs from the 1972 Prairie Repertory Theatre season. Plays were My Three Angels, Love Rides the Rails, You're a Good Man, Charlie Brown, and The Last of the Red Hot ...
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Advanced Science, EarlyView.The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang +11 more
wiley +1 more source
Prairie Repertory Theatre 1971 Season
, 1971 Programs, photographs and other material from the 1971 Prairie Repertory Theatre season. Included is an alumni list from 1970-1999, and photographs from the plays Harvey, Arsenic and Old Lace, and the Owl and the ...
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Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Advanced Science, EarlyView.The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang +12 more
wiley +1 more source
Освітній вимір, 2022 This article is an attempt to build individual space for younger pupils using the technology of repertory grids.
Z.M. Miroshnyk, O.Yu. Mykhaylenko
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Prairie Repertory Theatre 1979 Season
, 1978 Program and photograph from the 1979 Prairie Repertory Theatre season. Plays were Harvey, Send Me No Flowers, Damn Yankees, I Never Sang For My Father, and I Do! I Do!
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