Results 41 to 50 of about 14,675 (255)

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Measuring brand image: Shopping centre case studies [PDF]

, 2002
'Branding' is well known for consumer products but power has shifted from manufacturers' brands towards retailers'. The term 'image' is more common than 'brand' in the context of shopping centres, but 'branding' may become more important.
Cockett, T, Dennis, C, Marsland, D, Murphy, J, Patel, T   +4 more
core   +1 more source

Amido‐Amine Co(II) Precursor‐Based Atomic/Molecular Layer Deposition Processes for Cobalt‐Organic Thin Films and Their Thermal Conversion to CoO Thin Films

Advanced Materials Technologies, EarlyView.
Three new atomic/molecular layer deposition processes are developed for Co‐organic thin films using a promising all‐nitrogen‐coordinated cobalt precursor. The study examines film growth, reaction mechanisms, chemical stability, and decomposition pathways of the resulting films through extensive characterization techniques and DFT calculations ...
Topias Jussila, Jorit Obenlüneschloß, Ji Liu, Olga Partanen, Sami Vasala, Detlef Rogalla, Pieter Glatzel, Michael Nolan, Anjana Devi, Maarit Karppinen   +9 more
wiley   +1 more source

3D Printing of Soft Robotic Systems: Advances in Fabrication Strategies and Future Trends

Advanced Robotics Research, EarlyView.
Collectively, this review systematically examines 3D‐printed soft robotics, encompassing material selections, function integration, and manufacturing methodologies. Meanwhile, fabrication strategies are analyzed in order of increasing complexity, highlighting persistent challenges with proposed solutions.
Changjiang Liu, Bin Cui, Xumin Huang, Xiaoyu (Rayne) Zheng, T. Thang Vo‐Doan, Ruirui Qiao   +5 more
wiley   +1 more source

Cognitive representations of disability behaviours in people with mobility limitations : consistency with theoretical constructs [PDF]

, 2008
Disability is conceptualised as behaviour by psychological theory and as a result of bodily impairment by medical models. However, how people with disabilities conceptualise those disabilities is unclear.
Bandura A, Bandura A, Bellamy N, Diane Dixon, Ewart C K, Fransella F, Johnston M, Johnston M, Kelly G A, Leventhal H, Marie Johnston, Martin J, Patrick D L, Pollard B, Toshima M T, Ware J E, World Health Organization, World Health Organization   +17 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Giving the customer a voice: A study of market research methods and their perceived effectiveness in NPD [PDF]

, 2013
There is a widely held view that a lack of, “…customer understanding,” is one of the main reasons for product failure (Eliashberg et al., 1997, p. 219). This is despite the fact that new product development (NPD) is a crucial business process for many
Goffin, Keith, Michea, Adela, van der Hoven, Christopher, Varnes, Claus   +3 more
core  

Students’ perceptions of their psychiatric mental health clinical nursing experience: A personal construct theory exploration [PDF]

, 1999
Personal construct theory and repertory grid technique provides a suitable framework for exploring Registered Nursing students' perceptions of their psychiatric practicum.
Melrose, Sherri, Shapiro, Bonnie
core   +1 more source

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

CONSUMER VALUE IN APPAREL ONLINE MARKETING WITH REPERTORY GRID ANALYSIS [PDF]

Annals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2018
Online marketing has been increasing year by year and with the great advantages either for suppliers or consumers and e-business become more popular for any scale companies.
DEMIR MURAT, KILIC MUSA, ORHAN KEREM, KARASU GULBEN   +3 more
doaj