Results 41 to 50 of about 728 (209)

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Morphological variation in atlas and axis of Neotropical spiny rats (Rodentia, Echimyidae)

The Anatomical Record, EarlyView.
Abstract The unique morphologies of the first two cervical vertebrae, the atlas and axis, represent a significant innovation in mammalian evolution. These structures support the weight of the head and enable intricate movements of the head and neck.
Thomas Furtado da Silva Netto, João Felipe Leal Kaiuca, Adriana Itatí Olivares, William Corrêa Tavares   +3 more
wiley   +1 more source

Cortical Network Overconnectivity Relates to Sensory, Cognitive, and Social Dimensions in Young Children With Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT The heterogeneity in both the neurobiological mechanisms and the phenotypic presentations of autism spectrum disorder (ASD) poses a major challenge to clinical and translational research. Alterations in functional connectivity (FC) have been associated with ASD, yet it remains unclear whether and how divergent brain network properties may ...
Borja Rodríguez‐Herreros, Ahmad Mheich, Joana Maria Almeida Osório, Sonia Richetin, Vincent Junod, Lorène Arnold, Victoria Aeschbach, Lilia Nora Adamou, Katherina Gschwend, Laura Mendes, David Romascano, Paola Yu, Marine Jequier Gygax, Anne M. Maillard, Micah M. Murray, Mahmoud Hassan, Nadia Chabane   +16 more
wiley   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source

The role of wealth in the experience of quality of life of the semi–affluent investor

SA Journal of Industrial Psychology, 2006
In an attempt to assist semi-affluent investors’ best use their wealth to improve their lives, this study explores the role of wealth in the experience of quality of life.
L M Meyer, J S Uys
doaj   +1 more source

Bridging Academic Research and Business Practices at the Crossroad of Circular Economy and the SDGs

Business Strategy and the Environment, EarlyView.
ABSTRACT The global shift toward sustainability has amplified interest in the Circular Economy, which aims to optimize resource use and minimize waste. In parallel, the Sustainable Development Goals (SDGs) provide a universal framework for addressing social, environmental, and economic challenges.
Corentin Juin, Andrea Nicolodi
wiley   +1 more source

Identifying and Ranking Factors Affecting the Realization of Sustainable Production with a Shift from Industrial to Ecological Production(Case Study: Private Industrial Manufacturing Companies in Semnan) [PDF]

پژوهش‌های مدیریت عمومی, 2017
In general, sustainable progress is a landscape that simultaneously aims for social, economic, and environmental subjects, in the process of progress. In this course, production management and manufacturers are involved in sustainability more than ever. 
Mohammad Ali Shariat, Soleyman Iranzadeh, Alireza Bafandeh Zendeh   +2 more
doaj   +1 more source

Colonial and gendered peace: Decolonial perspectives on peace in Nagorno‐Karabakh

Feminist Anthropology, EarlyView.
Abstract This article critically interrogates peace processes in the aftermath of the First Nagorno‐Karabakh War by centering the lived experiences and political voices of Armenian and Azerbaijani internally displaced and refugee women, based on ethnographic fieldwork and in‐depth interviews conducted in 2019.
Ramil Zamanov
wiley   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

The impact of second language teacher education on the development of pre-service teachers’ pedagogical beliefs

Revista Lengua y Cultura
The current study explores the impact of second language teacher education (SLTE) on the development of the pedagogic beliefs held by fifty student-teachers enrolled in a public university in central Mexico.
Kenneth Richter
doaj   +1 more source