Results 201 to 210 of about 116,375 (241)

Chromosome-level genome assembly and annotation of Chinese herring (Ilisha elongata). [PDF]

open access: yesSci Data
Liu B   +11 more
europepmc   +1 more source

Synthesis of Versatile DNA‐Conjugated Aldehydes by Controlled Oxidation of Amines

open access: yesAngewandte Chemie, EarlyView.
A controlled oxidation strategy enables efficient in situ generation of aldehyde‐functionalized DNAs from DNA‐conjugated amines using O2/laccase/TEMPO. This approach facilitates reversible amine–aldehyde transformations for DNA bioconjugation, and provides access to chemically diverse DNA‐encoded libraries, broadening the toolbox for chemical biology ...
Guixian Zhao   +6 more
wiley   +1 more source

Enhancing Clinical Detection Accuracy of Large Structured Viral RNA via DNAzyme Cleavage and Antisense‐Assisted Rolling Circle Amplification

open access: yesAngewandte Chemie, EarlyView.
We show that antisense oligonucleotides can be used to restructure secondary structural elements around the circular DNA template binding sites of the genomic RNA for subsequent rolling circle amplification. This strategy was employed to identify otherwise COVID “false negative” saliva samples by accurately detecting the presence of SARS‐CoV‐2 genomic ...
Amal Mathai   +4 more
wiley   +1 more source

Synthesis of Chirally Chimeric Protein Nanoparticle Vaccines via Mirror‐Image Spy Chemistry

open access: yesAngewandte Chemie, EarlyView.
This study illustrates a versatile strategy for creating chirally chimeric protein constructs by merging natural‐chirality (L‐) and mirror‐image (D‐) protein motifs through a combination of L‐sortase‐mediated transpeptidation and D‐SpyStapler‐mediated ligation.
Songzi Kou   +4 more
wiley   +1 more source

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