Results 201 to 210 of about 82,762 (234)

Insights into the architecture of earthworm metallothionein genes, powered by long-read genomics and transcriptomics. [PDF]

NAR Genom Bioinform
Karpov MA, Short S, Kille P, Hobbs C, Etxabe AG, Spurgeon DJ, Stürzenbaum SR.   +6 more
europepmc   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Comparative analyses of the organelle genomes in Jacaratia spinosa (Caricaceae). [PDF]

Front Plant Sci
Zuo L, Lin Z, Chen H, Pan J, Zhu S, Ming R.   +5 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

A recent and rapid genome expansion driven by the amplification of transposable elements in the Neotropical annual killifish Garcialebias charrua. [PDF]

Biol Res
Gajardo-Escobar F, Valdivieso C, Di Genova A, Pereiro L, Arezo MJ, Nardocci G, Rojas N, Gutiérrez V, Papa NG, Berois N, Orellana A, Gutiérrez RA, González M, A Mendez M, Montecino M, Hodar C, Glavic A, Maass A, García G, Allende ML.   +19 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Inverted Alu repeats in loop-out exon skipping across hominoid evolution. [PDF]

Nucleic Acids Res
Denisko D, Kim J, Ku J, Zhao B, Lee EA.
europepmc   +1 more source

Chromosome-level genome assembly and annotation of the tropical sea cucumber Bohadschia ocellate. [PDF]

Sci Data
Huang Q, Wang X, Qin Z, Fan D, Ge H, Lin Y, Wang J, Yang Y, Xie Z, Huo D, Chen C, Qin H, Zhang X, Zhu X, Tang D, Ren C, Hu C, Chen T, Yan A.   +18 more
europepmc   +1 more source

Transcriptional PBR cycles at pericentromeric repeats cause gross chromosomal rearrangements through Rad52-dependent ADR-loop formation. [PDF]

Nucleic Acids Res
Xu R, Tang C, Wang JN, Motooka D, Tsubouchi H, Iwasaki H, Nakagawa T.   +6 more
europepmc   +1 more source

First Chromosome-level Genome Assembly and Annotation of an Endangered Freshwater Stingray (Fontitrygon garouaensis) from Africa. [PDF]

Sci Data
Nneji LM, Oladipo SO, Oyebanji OO, Ayoola AO, Omotoso O, Nneji IC, Adelakun KM.   +6 more
europepmc   +1 more source