Results 211 to 220 of about 25,814 (309)

Ultrasound Control of Gene Expression in Human iPSCs via Heat Shock Promoters

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 11, Page 3216-3228, November 2025.
ABSTRACT Inducible systems are crucial tools in biomedical research, offering researchers spatiotemporal control at the cellular level. A promising development in this field is the use of focused ultrasound for controlling gene expression using heat shock promoters (HSPs).
Alessandro R. Howells   +5 more
wiley   +1 more source

Patient Subgroups and Predictors of Improvement in Chronic Neuropathic Pain: A Trajectory‐Based Analysis

open access: yesEuropean Journal of Pain, Volume 29, Issue 10, November 2025.
ABSTRACT Background There is limited real‐world evidence on predictive factors for good outcomes in patients with chronic neuropathic pain (NP) treated in multidisciplinary tertiary care centres. This study aimed to identify subgroups of NP patients with similar pain trajectories and evaluate associated factors.
Xavier Moisset   +3 more
wiley   +1 more source

The Effects of Repeated Finger Flexion Movements on Self‐Reported Affect and Reward System Activation Are Weak and Inconsistent

open access: yesJournal of Clinical Psychology, Volume 81, Issue 11, Page 1095-1102, November 2025.
ABSTRACT Recent research has called into question the robustness and reliability of using body movements to activate motivational systems like approach‐reward. The purpose of the current studies was to test the effect of a repeated flexion movement task on approach‐reward system activation, positive and negative affect, and persistence on a difficult ...
Marissa R. Vander Missen   +8 more
wiley   +1 more source

Targeting TRPV4 to restore glymphatic system function and alleviate cerebral edema in ischemic stroke

open access: yesBrain Pathology, Volume 35, Issue 6, November 2025.
After ischemic stroke, TRPV4 activation induces cerebral edema through the TRPV4‐RhoA‐MMP9 axis: RhoA upregulates MMP9, which cleaves β‐DG to impair membrane anchoring. Subsequent β‐DG loss triggers AQP4 depolarization, disrupting GS‐mediated water homeostasis.
Yongchuan Li   +13 more
wiley   +1 more source

<b>Treatment of intractable neuropathic pain by high-frequency repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex </b>

open access: bronze, 2008
Koichi Hosomi   +8 more
openalex   +2 more sources

Transcranial Direct Current Stimulation in Parkinson's Disease Patients in the Off State: A Randomized Controlled Crossover Trial Examining the Effects on Pain With and Without the Influence of Dopaminergic Medication

open access: yesPain Practice, Volume 25, Issue 8, November 2025.
ABSTRACT Background tDCS has demonstrated hypoalgesic effects on Parkinson's disease (PD)‐related pain applied in the On state but not in the Off state. We aimed to determine the effect of tDCS in the Off state followed by dopaminergic medication on PD‐related pain.
Yeray González‐Zamorano   +4 more
wiley   +1 more source

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