Results 131 to 140 of about 1,081,239 (268)

Short- and long-term outcomes of systemic semilunar valve replacement in neonates and infants. [PDF]

NPJ Cardiovasc Health
Masri A, Shi CY, Winemiller B, Alsarrawi H, Kochilas LK, Reemtsen B, Qasim A, Rajab TK.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Reassessing BMI-based access to joint replacement surgery. [PDF]

PLoS Med
Evans JP, McLaughlin J, Evans JT.
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Valve-sparing root replacement with short saphenous vein interposition for left coronary artery reconstruction in redo type A aortic dissection: a case report. [PDF]

J Surg Case Rep
Kinoshita R, Watanabe T, Okaguchi K, Hirooka K.   +3 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Clamp On vs Off Impact of Distal Anastomotic Technique During Ascending Aortic Replacement in Acute Type A Aortic Dissection: IRAD Insights. [PDF]

Interdiscip Cardiovasc Thorac Surg
Pupovac SS, Jarral OA, Trimarchi S, Sultan I, Leshnower B, Desai ND, Sundt TM, Kachroo P, Li QG, Pai CW, Gleason TG, Patel HJ, Eagle KA, Brinster DR.   +13 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Clinical outcome of navigation-assisted knee arthroplasty (TKA) compared to in the same patients

Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, 2017
Jang-Won Park, Young-Hoo Kim, Jang-Won Park, Jun-Shik Kim   +3 more
doaj   +1 more source

Commentary: Revisiting the Question: Should We Avoid Valve Replacement in Children? [PDF]

J Chest Surg
Kwak JG.
europepmc   +1 more source