Results 261 to 270 of about 1,688,636 (315)

A polyphyodont, semiaquatic eutriconodontan mammal from the Early Cretaceous of China. [PDF]

Nat Commun
Bi S, Shi Y, Li Z, Rahmat SJ, Wang J, Wible JR.   +5 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Public Hearing Aid Policies in Brazil: Operational Gaps, Replacement Costs, and Data Governance in the Unified Health System (SUS). [PDF]

Int Arch Otorhinolaryngol
Bento RF, Gândara MER, Penteado SP.
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

High-Temperature Performance of Metakaolin-Based Geopolymer Recycled Mortar with Pumice Powder. [PDF]

Materials (Basel)
Zhu X, Jiang F, Chen C, Liu H, Zhu P, Li Y, Ma T.   +6 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Parental Preferences for Continuous Glucose Monitoring Devices in Children with Type 1 Diabetes: A Pilot Discrete Choice Experiment with Sensitivity Analysis of Decision Consistency. [PDF]

Patient Prefer Adherence
Liu Y, Huang J, Chen C, Wu J.
europepmc   +1 more source

Partial Replacement of Corn with Jackfruit Silage Maintains Productive Performance and Carcass Characteristics of Feedlot Lambs. [PDF]

Animals (Basel)
Salt MPF, Nascimento LS, Rodrigues HP, Ferreira JMS, Souza LL, Cruz CLDS, Silva RR, Carvalho GGP, Santos SA, Cabral ÍDS, Almeida FM, Azevêdo JAG.   +11 more
europepmc   +1 more source

Repaired tetralogy of Fallot across adulthood: from right ventricular remodelling to targeted intervention. [PDF]

Heart Fail Rev
Cienkowski K, Moll M, Cienkowska A, Kupczynska K, Banach M, Bielecka-Dabrowa A.   +5 more
europepmc   +1 more source

Long-Term Outcomes of Mitral Valve Repair with Limited Resection in Active Endocarditis. [PDF]

J Cardiovasc Dev Dis
Haidari Z, Turaev I, Demircioglu E, Knipp S.   +3 more
europepmc   +1 more source