Results 91 to 100 of about 1,484,991 (300)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
The completeness of national hip and knee replacement registers
Acta OrthopaedicaBackground and purpose: National joint replacement registries were developed for prospective monitoring of outcomes and post-market surveillance of implants. Increasingly registry data informs practice.
Jonathan M R French +16 more
doaj +1 more source
, 2011 My brother said it\u27s just withdrawal from the ecstasy. It\u27s such a high, he told me, that a normal low is so far down it\u27s like jumping off a building. Just don\u27t do it too often,he said. You might rewire your brain and your normal will never
Doak, Emily
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Current Features and Future Problems of the Italian Pension System [PDF]
The paper analyzes the issue of the financial sustainability of the Italian Pension System in the long-run, by discussing the main reforms occurred in the last few years and by examining some recent data: in particular, the data of the Italian Agency for
Scopelliti, Alessandro Diego
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Governance Control Mechanisms in Portuguese Agricultural Credit Cooperatives [PDF]
Over the last decade Portuguese Agricultural Credit Cooperatives (ACCs) have increasingly face survival challenges related to their difficulty in gathering equity. The main source of ACCs equity is the net benefit; thus, understanding how ACCs governance
Cabo, Paula, Rebelo, Joao
core +1 more source
No Californian Left Behind: Clean and Affordable Transportation Options for All Through Vehicle Replacement [PDF]
, 2014 As California focuses in on new, high-tech, best-in-class transportation strategies, it risks leaving behind an important subset of households and communities who could most benefit from the transition to a cleaner, cheaper, and more sustainable ...
Cole Wheeler, Jesse Morris, Kate Gordon
core
Unsupervised String Transformation Learning for Entity Consolidation
, 2018 Data integration has been a long-standing challenge in data management with many applications. A key step in data integration is entity consolidation. It takes a collection of clusters of duplicate records as input and produces a single "golden record ...
Abedjan, Ziawasch +9 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source