Results 121 to 130 of about 1,484,991 (300)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Were They Prepared for Retirement? Financial Status at Advanced Ages in the HRS and AHEAD Cohorts [PDF]
Many analysts have considered whether households approaching retirement age have accumulated enough assets to be well prepared for retirement. In this paper, we shift from studying household finances at the start of the retirement period, an ex ante ...
David A. Wise +2 more
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
NURE Investigación, 2010 Objective: To identify the factors associated with Health Related Quality of Life (HRQL), and Symptoms and Physical Functional Disability (S&PFD) after a Hip or Knee Total Replacement, according to a gender approach. A longitudinal cohort study design is
Sergio R. López Alonso +5 more
doaj
, 1980 Excerpt: In the last couple of years I have had several encounters with pastors and lay-leaders of Friends meetings who have been overwhelmingly impressed with a particular new hymnal.
Anderson, Paul N.
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
THE INVESTIGATION OF TURKISH SOCCER SUPER LEAGUE COACH CHANGES [PDF]
Pamukkale Spor Bilimleri Dergisi, 2010 The purpose of this study was to examine the replacements of the soccer coaches in the Turkish Professional Super league, between the year of 1997-2007, and how these replacements affect their teams.
Halit Egesoy
doaj
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Unemployment Compensation and High European Unemployment: A Reassessment with New Benefit Indicators [PDF]
Generous unemployment benefits lie at the heart of the conventional explanation for persistent high unemployment. The effects of benefit generosity are more ambiguous in a broader behavioral framework in which workers get substantial disutility from ...
David R. Howell, Miriam Rehm
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