Results 41 to 50 of about 1,484,991 (300)

What is broken? Expected lifetime, perception of brokenness and attitude towards maintenance and repair [PDF]

, 2015
This paper addresses the discrepancy between the expected and actual lifetimes of vacuum cleaners considering perceived ‘brokenness’ as a driver for replacement. Among electrical products, vacuum cleaners have a high rate of domestic ownership in the UK.
Barr, C, Cooper, T, Fisher, T, Harmer, L, Salvia, G   +4 more
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Preliminary results in tracheal replacement using stented aortic matrices for primary extensive tracheal cancerCentral MessagePerspective

JTCVS Techniques, 2023
Objective: Recent studies have demonstrated the feasibility and favorable long-term results of tracheobronchial replacement using stented cryopreserved aortic allografts.
Ilaria Onorati, MD, Dana M. Radu, MD, Ana Maria Santos Portela, MD, Marine Peretti, MD, Patrice Guiraudet, MD, Jeremy Bardet, MD, Olivia Freynet, MD, Morgane Didier, MD, Yurdagül Uzunhan, MD, PhD, Kader Chouahnia, MD, Boris Duchemann, MD, PhD, Valérian Bourinet, MD, Hervé Dutau, MD, PhD, Jean-Philippe Berthet, MD, PhD, Charles-Hugo Marquette, MD, PhD, François Tronc, MD, PhD, Myriam Locatelli Sanchez, MD, Christophe Trésallet, MD, PhD, Clément Fournier, MD, PhD, Nicolas Vénissac, MD, PhD, Makoto Miyara, MD, PhD, Eric Vicaut, MD, PhD, Emmanuel Martinod, MD, PhD   +22 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Retrospective Observational Analysis of Outcomes After Surgical Valve Replacement: A 15 Years' Experience in a Tertiary Care Hospital

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2023
Background: None of the currently available prosthetic valves are comparable to native valves in hemodynamic functions. One has to choose between durability, thrombogenicity, or risk of major bleeds.
Mandeep Singh Sondh, Rajiv Gupta, Sidhant Sachdeva, Rohit Tandon   +3 more
doaj   +1 more source

Four-Letter Super Connoisseur\u27s Ladders [PDF]

, 2001
Four-letter words are famously well connected to each other. Fewer than one per cent of words connect to no other, whereas over 70 per cent in each of the four possible positions-on average, there are 23 neighbours for each word.
Gooch, Rex
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Distal Femoral Replacement Following an Intraoperative Periprosthetic Fracture in a Patient with Prior Bone Mulch ACL Reconstruction

Case Reports in Orthopedics, 2019
Periprosthetic distal femur fractures can be treated nonoperatively, with open reduction and internal fixation or with more constrained prostheses. Distal femoral replacement is typically a last resort treatment option for comminuted periprosthetic or ...
Anthony Gemayel, Matthew J. Yousif, William Padget, Joseph Finch   +3 more
doaj   +1 more source

Least Recently Used Page Replacement using Last Use Distance (LRUL)

International Journal of Computer Applications, 2013
Virtual memory technique is used in modern OS which permits the execution of a program while it is partially available in memory thus providing an illusion of very large memory to the user and freeing the user from the concern of large program size.
Narendra Teotia, Ruchin Gupta
openaire   +1 more source

Missing Women and Bare Branches: Gender Balance and Conflict [PDF]

, 2005
The emerging subfield of “security demographics” examines the linkages between population dynamics and the security trajectories of nation-states.
den Boer, Andrea, Hudson, Valerie M
core