Results 51 to 60 of about 1,484,991 (300)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Dalbavancin to Treat Infected Massive Endoprostheses: A Case Report and Cost Comparison Analysis [PDF]
Journal of Bone and Joint Infection, 2019 We report a case of an infected massive endoprosthetic replacement treated successfully with 2 stage surgery and off-label dalbavancin. Dalbavancin was used due to a limited number of antimicrobial options that could be administered safely in an ...
T. Azamgarhi +3 more
doaj +1 more source
陆军军医大学学报, 2022 Objective To evaluate the mid-term clinical efficacy of total hip replacement using a standardized 3D printed porous trabecular titanium acetabular cup. Methods Clinical data of 23 consecutive patients undergoing total hip replacement with a standardized
LIU Chen, ZHANG Ke, YANG Bin
doaj +1 more source
Core-aware Cache Replacement Policy for Reconfigurable Last Level Cache
Journal of the Korea Society of Computer and Information, 2013 In multi-core processors, Last Level Cache(LLC) can reduce the speed gap between the memory and the core. For this reason, LLC has big impact on the performance of processors. LLC is composed of shared cache and private cache. In computer architecture community, most researchers have mainly focused on the management techniques for shared cache, while ...
Dong-Oh Son +3 more
openaire +2 more sources
On the inclusion probabilities in some unequal probability sampling plans without replacement
, 2012 Comparison results are obtained for the inclusion probabilities in some unequal probability sampling plans without replacement. For either successive sampling or H\'{a}jek's rejective sampling, the larger the sample size, the more uniform the inclusion ...
Yu, Yaming
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
New Markets for Local Experts in Africa? [PDF]
In the past decades the involvement of local experts in the planning and evaluation of development projects has steadily increased. Ownership of development planning is propagated as major aim of bilateral and international development co-operation. Yet,
Kohnert, Dirk
core +4 more sources
The Last Mile in Beta-Cell Replacement Therapy for Type 1 Diabetes: Time to Grow Up
Transplant InternationalBeta cell replacement therapy for type 1 diabetes (T1D) is undergoing a transformative shift, driven by advances in stem cell biology, gene editing, and tissue engineering.
Lorenzo Piemonti, Lorenzo Piemonti
doaj +1 more source
Lower limb joint repair and replacement: an overview [version 1; peer review: 2 approved]
F1000Research, 2019 In the last few years, much has been published concerning total joint arthroplasty, and debates and discussions to new questions and points of view started many years ago. In this commentary, we report the latest evidence of best practice in the field of
Rocco Aicale, Nicola Maffulli
doaj +1 more source
Replacing the Irreplaceable: Fast Algorithms for Team Member Recommendation [PDF]
, 2014 In this paper, we study the problem of Team Member Replacement: given a team of people embedded in a social network working on the same task, find a good candidate who can fit in the team after one team member becomes unavailable.
Buchler, Norbou +5 more
core +2 more sources