Results 121 to 130 of about 1,865,365 (306)

Research on the Impact of the Optimal State-owned Capital Allocation, Tax Deferral and Delayed Retirement on the Replacement Rate of Pension and Policy Optimization

SAGE Open
In order to cope with the aging population, China has implemented individual tax deferred policy and state-owned capital allocation, and plans to raise the retirement age.
Yixin Gao, Wenguang Yu, Guofeng Guan, Xiaoqiang Wu, Shuanming Li   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Demographic Change, Institutional Settings, and Labor Supply [PDF]

This paper analyzes cross-country panel data to examine the effect of key institutional features of social security systems on male labor supply. Our findings indicate that the labor supply of older males covaries negatively with replacement rates and ...
David Canning, David E. Bloom, Günther Fink, Jocelyn E. Finlay   +3 more
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

AN ECONOMIC ASSESSMENT OF WETLAND MITIGATION IN NORTHWEST MINNESOTA [PDF]

The economic efficiency of wetland mitigation in Minnesota's Red River Valley was examined using the Minnesota Routine Assessment Method on ten wetland case studies to rate the functions of impacted and replacement wetlands.
Leitch, Jay A., Meyer, Aaron J., Sip, Robert L.   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Tooth replacement in the early-diverging neornithischian Jeholosaurus shangyuanensis and implications for dental evolution and herbivorous adaptation in Ornithischia

BMC Ecology and Evolution
Background Tooth replacement patterns of early-diverging ornithischians, which are important for understanding the evolution of the highly specialized dental systems in hadrosaurid and ceratopsid dinosaurs, are poorly known.
Jinfeng Hu, Xing Xu, Fuqiang Li, Fenglu Han   +3 more
doaj   +1 more source

How increased heifer growth rate and reduced dairy cow replacement rate can improve farm economy and reduce greenhouse gas emissions - a win to win situation?

Animal
Rearing of replacement heifers makes up a significant part of the total costs in dairy farming. Nevertheless, the average age at first calving for dairy heifers still stays well above 2 years in many countries.
J.K. Sommerseth, S. Shrestha, M. MacLeod, A. Hegrenes, B.G. Hansen, R. Salte   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Source of Finance for Social Security Reform with Redistribution [PDF]

This study investigates the welfare implications of social security reforms in Japan. Based on the overlapping generations model with idiosyncratic income risk, we consider four social security reform plans: (1) gradual reduction in the replacement rate ...
Yamada, Tomoaki
core