Results 51 to 60 of about 1,865,365 (306)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Effect of non-genetic factors on replacement rate and its components in Murrah buffaloes of Tamil Nadu

open access: yesIndian Journal of Animal Sciences, 2014
The average value (in %) for abnormal birth, male birth, female birth, death of female calves, culling of female calves, replacement rate on basis of total pregnancies and total female calves born were 2.82, 51.4, 48.6, 38.8, 21.2, 19.4 and 40.0 ...
A K THIRUVENKADAN, P DEVENDRAN
doaj   +1 more source

Design and Performance of Ultrathin Overlay Epoxy-Rubber Concrete

open access: yesAdvances in Materials Science and Engineering, 2021
Epoxy-rubber concrete has a big potential to be used for pavement overlays, but there is currently no appropriate epoxy-rubber concrete design method and process.
Qi Huang, Fei Chen
doaj   +1 more source

Universally Typical Sets for Ergodic Sources of Multidimensional Data [PDF]

open access: yes, 2013
We lift important results about universally typical sets, typically sampled sets, and empirical entropy estimation in the theory of samplings of discrete ergodic information sources from the usual one-dimensional discrete-time setting to a ...
Krueger, Tyll   +3 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Pension Security Level of Urban Employees in China Based on CHIPs

open access: yesDiscrete Dynamics in Nature and Society, 2022
In 2019, the Chinese government has put forward comprehensive plan for reducing social insurance premium rate, which will affect the measurement of the pension security level.
Chengyu Gao, Yake Wang
doaj   +1 more source

Influence of Curing Age and Mix Composition on Compressive Strength of Volcanic Ash Blended Cement Laterized Concrete [PDF]

open access: yes, 2012
This study investigates the influence of curing age and mix proportions on the compressive strength of volcanic ash (VA) blended cement laterized concrete. A total of 288 cubes of 100mm dimensions were cast and cured in water for 3, 7, 28, 56, 90 and 120
Babafemi, A. J   +2 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Benefit from regular versus leakage-related exchange of voice prostheses in patients post-laryngectomy considering complication rates and patient satisfaction feedback—a randomized case−controlled trial

open access: yesFrontiers in Oncology
ObjectiveThe complications related to voice prosthesis usage substantially affect the physical and social functioning of patients after total laryngectomy, which influences their quality of life.
Michał Żurek   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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