Results 71 to 80 of about 1,865,365 (306)
Journal of Marine Science and EngineeringCarbon-fiber-reinforced polymer (CFRP) is a composite material consisting of a resin matrix reinforced with carbon fibers. This study focuses on CFRP composite pipe piles as the subject of investigation, exploring the impact of substituting steel bars ...
Wei Zhang, Wei Shao, Yinghui Nie
doaj +1 more source
Lifetime Uncertainty and the Optimal Replacement Rate of urban Public Pension in China [PDF]
By considering lifetime uncertainty, this paper employs an OLG model within general equilibrium framework to analyze China’s urban public pension system.
Yang, Zaigui
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Evolution of high tooth replacement rates in theropod dinosaurs.
PLoS ONE, 2019 Tooth replacement rate is an important contributor to feeding ecology for polyphyodont animals. Dinosaurs exhibit a wide range of tooth replacement rates, mirroring their diverse craniofacial specializations, but little is known about broad-scale ...
Michael D D'Emic +5 more
doaj +1 more source
Job Protection and Wage Replacement: Key Factors in Take Up of Paid Family and Medical Leave Among Lower-Wage Workers [PDF]
, 2019 In this brief, author Kristin Smith discusses two key factors—job protection and sufficient wage replacement—that influence take up of paid family and medical leave among lower-wage workers.
Smith, Kristin
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Modelling the impact of sow replacement rate on farm performance [PDF]
Revista Brasileira de ZootecniaThis study aimed to develop and assess a deterministic mathematical model for predicting the impacts of varying sow replacement rates on the performance of farms producing weaned piglets. Initially, the influence of replacement rate on herd structure was
Henrique da Costa Mendes Muniz +5 more
doaj +1 more source
Social Security Replacement Rates for Alternative Earnings Benchmarks [PDF]
Social Security reform proposals are often presented in terms of their differential impacts on hypothetical or ‘example’ workers. Our work explores how different benchmarks produce different replacement rate outcomes.
John W.R. Phillips, Olivia S. Mitchell
core
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source