Results 101 to 110 of about 48,372 (292)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Kempelen’s speaking machine: Experiences with replicas [PDF]
, 2017 There are a number of recent replicas of Wolfgang von Kempelen's speaking machine. Although all of them are explicitly based on Kempelen's own description nearly none of them are identical in construction and sound.
Gósy, Mária, Brackhane, Fabian
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Detecting near replicas on the Web by content and hyperlink analysis [PDF]
, 2003 The presence of replicas or near-replicas of documents is very common on the Web. Whilst replication can improve information accessibility for the users, the presence of near-replicas can hinder the effectiveness of search engines. We propose a method to
Marco Maggini +9 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Behaviour of ultrasonic waves in porous rigid materials: anisotropic Biot-Attenborough model [PDF]
, 2014 The anisotropic pore structure and elasticity of cancellous bone cause wave speeds and attenuation in cancellous bone to vary with angle. Anisotropy has been introduced into Biot theory by using an empirical expression for the angle-and porosity ...
Aygun, Haydar
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Analysis of technical replicas (MALDI Biotyper 3.1 classification). [PDF]
, 2015 Analysis of technical replicas (MALDI Biotyper 3.1 classification).
Winfried Hofmann (690872) +7 more
core +1 more source