Results 181 to 190 of about 35,071 (244)

Platform competition and strategic trade‐offs for complementors: Heterogeneous reactions to the entry of a new platform

Strategic Management Journal, EarlyView.
Abstract Research Summary We study how the entry of a rival platform affects the strategies of the incumbent's complementors. The latter face a trade‐off: While the entry threatens their benefits from indirect network effects, it also allows them to escape intense within‐platform competition.
Johannes Loh, Ambre Elsas‐Nicolle
wiley   +1 more source

Retro-inversion imparts antimycobacterial specificity to host defense peptides. [PDF]

Nat Commun
Glossop HD, Gebretsadik G, Sultana S, Biswas D, Schacht NA, Yennawar NH, Rather MA, Baughn AD, Medina SH.   +8 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response. [PDF]

Nat Commun
Matsuda K, Harrison M, Wettstein E, Pederson J, Pullano AA, Bolkhovitinov L, Kim B, Steinberg I, Griesman T, Stuccio S, Rogan D, Patamawenu A, Shofner T, Wright NE, Webber JD, Van't Veer F, Roenicke R, Koory E, Roeder PM, Ober E, Leach B, Tsybovsky Y, Stephens T, Del Moral-Sanchez I, Bontjer I, McGinnes-Cullen LW, Chu E, Liang J, Torres JL, Lin RN, Tran AS, Dziubla G, Serebryannyy L, Narpala S, Lin B, Castro M, Ozorowski G, Ward AB, Sanders RW, Kwong PD, Guenaga J, Wyatt R, Morrison T, Connors M.   +43 more
europepmc   +1 more source

Teaching financial crises: A leverage experiment

Southern Economic Journal, EarlyView.
Abstract College students often struggle to understand the prevalence of asset price bubbles and the difficulty of timing asset purchases and sales. Even economics students are consistently surprised when bubbles burst. These breaks can have real macroeconomic effects, particularly when the price surge is fueled by leverage.
Lee Coppock, Daniel Harper, Charles Holt
wiley   +1 more source

Programmable self-replicating JEV nanotherapeutics redefine RNA delivery in ALS. [PDF]

Commun Biol
Loo YS, Yusoh NA, Yap K, Ng CS.
europepmc   +1 more source

On the preservation of reinforced concrete architectural masterpieces: The challenges of the REcube project

Structural Concrete, EarlyView.
Abstract The preservation of reinforced concrete masterpieces from the 20th century poses a complex challenge. These structures often combine architectural, historical, and technological value, which standard engineering codes and conservation practices are not fully equipped to address. The Erasmus+ REcube project responded to this gap by promoting an
Elisabetta Margiotta Nervi, Giulio Zani, Marco di Prisco   +2 more
wiley   +1 more source

DNA replication timing reveals genome-wide features of transcription and fragility. [PDF]

Nat Commun
Berkemeier F, Cook PR, Boemo MA.
europepmc   +1 more source

Measuring the interest rate risk of Belgian regulated savings deposits [PDF]

Konstantijn Maes, Thierry Timmermans
core  

Addressing Complexity in System of Systems With GraphRAG: An AI‐Driven Framework for Dynamic Data Integration

Systems Engineering, EarlyView.
ABSTRACT System of Systems (SoS) environments are inherently complex, involving numerous operationally and managerially independent component systems with hidden interdependencies and frequent interactions based on unstructured data. In this paper, we propose using graphical Retrieval‐Augmented Generation (GraphRAG), a tool that combines large language
Yinchien Huang, Tien‐Yueh Fung, Daniel A. DeLaurentis   +2 more
wiley   +1 more source