Results 251 to 260 of about 76,259 (304)

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability. [PDF]

Mol Cell
Bai G, Endres T, Kühbacher U, Mengoli V, Greer BH, Peacock EM, Newton MD, Stanage T, Dello Stritto MR, Lungu R, Crossley MP, Sathirachinda A, Cortez D, Boulton SJ, Cejka P, Eichman BF, Cimprich KA.   +16 more
europepmc   +1 more source

H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours. [PDF]

Nat Commun
Dibitetto D, Liptay M, Vivalda F, Dogan H, Gogola E, González Fernández M, Duarte A, Schmid JA, Decollogny M, Francica P, Przetocka S, Durant ST, Forment JV, Klebic I, Siffert M, de Bruijn R, Kousholt AN, Marti NA, Dettwiler M, Sørensen CS, Tille JC, Undurraga M, Labidi-Galy I, Lopes M, Sartori AA, Jonkers J, Rottenberg S.   +26 more
europepmc   +1 more source

A RAD18-UBC13-PALB2-RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells. [PDF]

Nucleic Acids Res
Cybulla E, Wallace S, Meroni A, Jackson J, Agashe S, Tennakoon M, Limbu M, Quinet A, Lomonosova E, Noia H, Tirman S, Wood M, Lemacon D, Fuh K, Zou L, Vindigni A.   +15 more
europepmc   +1 more source

Life at the replication fork: A scientific and personal journey. [PDF]

J Biol Chem
McHenry CS.
europepmc   +1 more source

Replication fork stalling in late S-phase elicits nascent strand degradation by DNA mismatch repair. [PDF]

Nucleic Acids Res
Colicino-Murbach E, Hathaway C, Dungrawala H.   +2 more
europepmc   +1 more source

Correction: Reversion from basal histone H4 hypoacetylation at the replication fork increases DNA damage in FANCA deficient cells. [PDF]

PLoS One
García-de-Teresa B, Ayala-Zambrano C, González-Suárez M, Molina B, Torres L, Rodríguez A, Frías S.   +6 more
europepmc   +1 more source

DNA replication fork stabilization and restart mechanisms revealed by biochemical reconstitution

Canal B, Bertolin AP, Lee GC, Minamino M, Diffley JF.   +4 more
europepmc   +1 more source