Results 191 to 200 of about 1,003,936 (218)

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

A replication study of novel fetal hemoglobin-associated genetic variants in sickle cell disease-only cohorts. [PDF]

Hum Mol Genet
Ilboudo Y, Brosseau N, Lo KS, Belhaj H, Moutereau S, Marshall K, Reid M, Kutlar A, Ashley-Koch AE, Telen MJ, Joly P, Galactéros F, Bartolucci P, Lettre G.   +13 more
europepmc   +1 more source

Intersectionality matters for hispanic health: A replication study using the All of Us Research Program. [PDF]

Int J Equity Health
Rodrigues M, Risner E, Rhodes-Bratton B, Cook SH, Cuevas A.   +4 more
europepmc   +1 more source

The Effects of Augmented Feedback, Focus of Attention, and Monetary Reward on Vertical Jump Height: A Replication Study. [PDF]

Int J Exerc Sci
Bakhshinejad J, Hutchinson J, Murphy J, Trainor L, Friedman S, Coker N.   +5 more
europepmc   +1 more source

A longitudinal replication study testing migration from video game loot boxes to gambling in British Columbia, Canada. [PDF]

BMC Psychol
Palmer L, Brooks GA, Clark L.
europepmc   +1 more source

Childhood Cigarette Smoking and Risk of COPD in Older United States Adults: A Nationally Representative Replication Study. [PDF]

Chronic Obstr Pulm Dis
Ozga JE, Sargent JD, Steinberg AW, Tang Z, Stanton CA, Paulin LM.   +5 more
europepmc   +1 more source

Longitudinal brain structure changes in Parkinson's disease: A replication study. [PDF]

PLoS One
Sokołowski A, Bhagwat N, Chatelain Y, Dugré M, Hanganu A, Monchi O, McPherson B, Wang M, Poline JB, Sharp M, Glatard T.   +10 more
europepmc   +1 more source

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Replication stress as a trigger for cell extrusion

Nature Reviews Molecular Cell Biology, 2021
Paulina Strzyz
exaly  

Maintaining genome stability at the replication fork

Nature Reviews Molecular Cell Biology, 2010
Dana Branzei, Marco Foiani
exaly