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Commentary on the article Georgescu, R. et al. Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Nataliya Petryk
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Replisome components—Post-translational modifications and their effects
The process of DNA replication is highly regulated, but at the same time very dynamic. Once S-phase is initiated and replication elongation is occurring, the cells are committed to complete replication in order to ensure genome stability and survival ...
Zech, Juergen, Dalgaard, Jacob Z.
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Structure of a human replisome shows the organisation and interactions of a DNA replication machine [PDF]
The human replisome is an elaborate arrangement of molecular machines responsible for accurate chromosome replication. At its heart is the CDC45-MCM-GINS (CMG) helicase, which, in addition to unwinding the parental DNA duplex, arranges many proteins ...
Joseph T P Yeeles +2 more
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Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases
Trends in Genetics, 2021Simon Boulton, Roberto Bellelli
exaly
Single-molecule mapping of replisome progression
Molecular Cell, 2022Clémence Claussin +2 more
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Processive Activity of Replicative DNA Polymerases in the Replisome of Live Eukaryotic Cells
Molecular Cell, 2020Rodrigo Reyes-Lamothe +2 more
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Replisome activity slowdown after exposure to ultraviolet light in Escherichia coli
Proceedings of the National Academy of Sciences of the United States of America, 2019Rodrigo Reyes-Lamothe, Andrea Wang
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Replisome bypass of a protein-based R-loop block by Pif1
Proceedings of the National Academy of Sciences of the United States of America, 2020Michael O'Donnell +2 more
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T7 replisome directly overcomes DNA damage
Nature Communications, 2015Michelle D. Wang +2 more
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