Results 151 to 160 of about 105,162 (327)

Age‐related penetrance of phospholamban p.Arg14del cardiomyopathy

European Journal of Heart Failure, EarlyView.
Age‐related penetrance of phospholamban (PLN) p.Arg14del cardiomyopathy. ECG, electrocardiogram; ICD, implantable cardioverter‐defibrillator; LVAD, left ventricular assist device; LVEF, left ventricular ejection fraction; MRI, magnetic resonance imaging; PVC, premature ventricular contraction; SCD, sudden cardiac death; VF, ventricular fibrillation; VT,
Tom E. Verstraelen, Freyja H.M. van Lint, Remco de Brouwer, Virginnio M. Proost, Esmee van Drie, Laurens P. Bosman, Lotte Weverink, Karim Taha, Thais Bueren, Aeilko H. Zwinderman, Cathelijne Dickhoff, Toon Oomen, Bas A. Schoonderwoerd, Tjeerd Germans, Arjan C. Houweling, Juan R. Gimeno‐Blanes, Folkert W. Asselbergs, Paul A. van der Zwaag, Anneline S.J.M. te Riele, Rudolf A. de Boer, Maarten P. van den Berg, J. Peter van Tintelen, Arthur A.M. Wilde   +22 more
wiley   +1 more source

Secondary repolarization changes in patients with left ventricular hypertrophy

Терапевтический архив, 2010
Aim. To estimate the detection rate of tension syndrome and nonspecific repolarization changes in patients with arterial hypertension (AH). Subjects and methods. The electrocardiograms of 234 patients with AH (104 males and 130 females) were analyzed, by
Elena Valentinovna Blinova, Galina Vladimirovna Ryabykina, Tamara Anatol'evna Sakhnova, E V Blinova, G V Ryabykina, T A Sakhnova   +5 more
doaj  

Short-term Variability of Repolarization Is Superior to Other Repolarization Parameters in the Evaluation of Diverse Antiarrhythmic Interventions in the Chronic Atrioventricular Block Dog

, 2017
Alexandre Bossu, Rosanne Varkevisser, Henriëtte D.M. Beekman, Marien J. C. Houtman, Marcel A. G. van der Heyden, Marc A. Vos   +5 more
openalex   +1 more source

Comparative analysis of myocardium repolarization abnormalities in female biathlon athletes with different fitness levels [PDF]

, 2018
Alexander Bolotin, Vladislav Bakayev, Chunguang You   +2 more
openalex   +1 more source

Regulatory Effect and Mechanism of Tanshinone I on Cell Apoptosis in Steroid‐Induced Osteonecrosis of the Femoral Head

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Steroid‐induced osteonecrosis of the femoral head (SIONFH) is a debilitating orthopedic condition. This study investigated the mechanism of Tanshinone I (TsI) in SIONFH modulating apoptosis in SIONFH via the PI3K/AKT/mTOR pathway. A SIONFH rat model was treated with TsI and a PI3K activator. Bone mineral density (BMD), bone volume/total volume
Qing Su, Jia Chen
wiley   +1 more source

Relative Efficiency of Depolarization and Repolarization of the Myocardium Determined from the Spatial Vectorcardiogram [PDF]

, 1955
Charles E. Kossmann, Stanley A. Briller, Nathan Marchand   +2 more
openalex   +1 more source

Fabrication of Lithium/Strontium‐Releasing Smart Bioactive Glasses with Anti‐Inflammatory and Osteogenic Effects Tailored to Pathological Stages

Macromolecular Bioscience, EarlyView.
Bioactive glasses with controllable dual ion release capability are developed to aid bone regeneration. The bioactive glasses rapidly release lithium ions that exert an anti‐inflammatory effect, suppressing inflammation after bone injury. Simultaneously, the bioactive glasses slowly release strontium ions, which support bone formation by suppressing ...
Hirohiko Sakai, Jun‐Ichi Sasaki, Haruaki Kitagawa, Gabriela L. Abe, Tomoki Kohno, Naoya Funayama, Satoshi Imazato   +6 more
wiley   +1 more source

Proteomic Biomarkers Are Linked to QTc Interval in Patients With Chronic Heart Failure

PROTEOMICS – Clinical Applications, EarlyView.
ABSTRACT Objective This study investigates the link between circulating proteins and rate‐corrected QT (QTc) interval in patients with heart failure with reduced ejection fraction (HFrEF) and their association with cardiovascular outcomes. Methods and Results We analyzed 197 HFrEF patients from the prospective Serial Biomarker Measurements and New ...
Mylène Barry‐Loncq de Jong, Teun B. Petersen, Sabrina Abou Kamar, Navin Suthahar, Nick van Boven, K. Martijn Akkerhuis, Peter J. van der Spek, Peter D. Katsikis, Rudolf A. de Boer, Victor A. W. M. Umans, Eric Boersma, Folkert W. Asselbergs, Jasper J. Brugts, Sing‐Chien Yap, Isabella Kardys   +14 more
wiley   +1 more source

Mitral valve repair results in suppression of ventricular arrhythmias and normalization of repolarization abnormalities in mitral valve prolapse [PDF]

, 2018
Wael Alqarawi, David H. Birnie, Ian G. Burwash   +2 more
openalex   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source