Results 151 to 160 of about 100,632 (325)

Advanced extracellular vesicle immunotherapy

FlexMat, EarlyView.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang, Yunfei Mu, Xianyue Ji, Xiaoting Jiang, Ruiheng Wang, Xianguang Ding, Lianhui Wang   +6 more
wiley   +1 more source

Sequential ultrasound‐driven dynamic control of macrophage polarization combined with hydrogel for mechano‐chemical synergistic tissue repair

Interdisciplinary Medicine, EarlyView.
This study presents an innovative therapeutic strategy that integrates sequential ultrasound therapy with an injectable oxidized dextran‐metformin (ODE‐Met) hydrogel to dynamically regulate macrophage polarization and promote angiogenesis for inflamed tissue repair.
Fulong Man, Kun Wang, Zichen Yang, Lulu An, Caoyi You, Rongjie Li, Yanni Cai, Yang Li, Li Chen, Yiqiong Liu, Yan Li, Haiqing Dong, Yongyong Li   +12 more
wiley   +1 more source

Biomarkers for the estimation of isoproterenol‐induced myocardial infarction: A review of key parameters

Journal of Intelligent Medicine, EarlyView.
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran, Tarique Mahmood, Farogh Ahsan, Shahzadi Bano, Vaseem Ahamad Ansari, Mohd Adnan   +5 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Secondary repolarization changes in patients with left ventricular hypertrophy

Терапевтический архив, 2010
Aim. To estimate the detection rate of tension syndrome and nonspecific repolarization changes in patients with arterial hypertension (AH). Subjects and methods. The electrocardiograms of 234 patients with AH (104 males and 130 females) were analyzed, by
Elena Valentinovna Blinova, Galina Vladimirovna Ryabykina, Tamara Anatol'evna Sakhnova, E V Blinova, G V Ryabykina, T A Sakhnova   +5 more
doaj  

Feasibility of High‐Density Surface Electromyography for the Detection of Neuromuscular Disorders in Children

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Diagnosing neuromuscular disorders in children is challenging. Concentric needle electromyography (CNEMG) is the standard for electrophysiological assessments but has limitations in pediatric populations. High‐density surface electromyography (HDsEMG) provides a noninvasive technique with superior spatial resolution, enabling
Eduardo Martinez‐Valdes, Ignacio Contreras‐Hernandez, Ragul Selvamoorthy, Francesco Negro, Andrew Lawley   +4 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Traditional and novel electrocardiographic conduction and repolarization markers of sudden cardiac death

Europace, 2017
G. Tse, B. Yan
semanticscholar   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Sudden cardiac arrest associated with early repolarization.

New England Journal of Medicine, 2008
M. Haïssaguerre, N. Derval, F. Sacher, L. Jesel, I. Deisenhofer, L. De Roy, J. Pasquié, A. Nogami, D. Babuty, S. Yli-mayry, C. de Chillou, P. Scanu, P. Mabo, Seiichiro Matsuo, V. Probst, S. Le Scouarnec, P. Defaye, J. Schlaepfer, T. Rostock, D. Lacroix, D. Lamaison, T. Lavergne, Y. Aizawa, A. Englund, F. Anselme, M. O'Neill, M. Hocini, K. Lim, S. Knecht, G. Veenhuyzen, P. Bordachar, M. Chauvin, P. Jais, G. Coureau, G. Chêne, G. Klein, J. Clémenty   +36 more
semanticscholar   +1 more source