Detecting Local Myocardial Spatiotemporal Repolarization Gradients With Clinical Mapping Arrays. [PDF]
Subha T +11 more
europepmc +1 more source
Genetic risk factor identification for common epilepsies guided by integrative omics data analysis
Abstract Objective Genetic generalized epilepsies (GGEs) comprise the most common genetically determined epilepsy syndromes, following a complex mode of inheritance. Although many important common and rare genetic factors causing or contributing to these epilepsies have been identified in the past decades, many features of the genetic architecture are ...
Ashwini Mushunuri +9 more
wiley +1 more source
Sex Hormones and Repolarization Dynamics During the Menstrual Cycle in Women Treated With QT-Prolonging Drugs. [PDF]
San A +11 more
europepmc +1 more source
Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa +17 more
wiley +1 more source
ABSTRACT Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. Its incidence increases significantly with age and has become a major global public health issue. Although research into the mechanisms of AF has spanned over a century‐ranging from the reentry theory to the rotor hypothesis‐none of these
Xin Chu +4 more
wiley +1 more source
Effect of scar distribution on transmural and planar repolarization gradients and dispersion in non-ischemic cardiomyopathies with ventricular arrhythmias. [PDF]
Tonko JB +5 more
europepmc +1 more source
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams +6 more
wiley +1 more source
Strategies for prolonging ventricular action potential duration without increasing transmural dispersion of repolarization. [PDF]
Cabo C.
europepmc +1 more source
17β-Estradiol Does Not Designate Non-Sex-Specific Early Ventricular Arrhythmia in Acute Myocardial Infarction, in Contrast to C-Reactive Protein. [PDF]
Semedzhieva NE +4 more
europepmc +1 more source

