Results 181 to 190 of about 57,164 (287)

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

Corrigendum: The Electrogenic Na+/K+ Pump Is a Key Determinant of Repolarization Abnormality Susceptibility in Human Ventricular Cardiomyocytes: A Population-Based Simulation Study

Frontiers in Physiology, 2017
Oliver J. Britton, Alfonso Bueno-Orovio, László Virág, András Varró, Blanca Rodriguez   +4 more
doaj   +1 more source

When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial-Associated Cardiomyopathy Mimicking Lupus Myocarditis. [PDF]

Clin Case Rep
Covo DAP, Beltrán MCB, Ortega DA, Bueno COP, Guardela EJJ, Calderón CH, Méndez EAC, Álvarez LVO, Correa AM, Peña ÁAG.   +9 more
europepmc   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Macroscopic T-Wave Alternans in QTc Prolongation: A Warning Sign Before Torsades de Pointes. [PDF]

JACC Case Rep
Kamble AA, Doss R, Jaiswal J, Gupta A.
europepmc   +1 more source

Effect of chitosan‐containing desensitizers applied prior to bleaching on the physical properties of enamel

European Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the effects of adding chitosan (Chi) to desensitizing agents applied before dental bleaching on enamel properties. Bovine enamel specimens were allocated to seven groups (n = 12): no treatment (negative control), 2% NaF (positive control), 2% NaF + 2% Chi, 2% NaF + 5% Chi, 2% NaF + 5% KNO3, 2% NaF + 5% KNO3 + 2 ...
Júlia Barbato, Luís Otávio Passos, Carolina Meneghin Barbosa, Marcos Roberto de Lima Benati, Renata Siqueira Scatolin, Ana Carolina Cabral Roque, Tatiane Cristina Dotta, Waldemir Francisco Vieira‐Junior, Laura Nobre Ferraz   +8 more
wiley   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

Brugada Syndrome in the Pediatric Population: Diagnostic Challenges and Clinical Outcome—Results of the German Multicenter Study COGIA

Journal of Cardiovascular Electrophysiology, EarlyView.
The study examines 76 patients of the German multicenter study COGIA with suspected BrS in 12 centers in Germany. Thirty‐nine patients met the current ESC diagnostic criteria, 34 of whom met the Shanghai Score criteria. Four major arrhythmic events (ACA, SCD, appropriate ICD shock) occurred in the cohort (5.3%), all in the group of patients fulfilling ...
Lea Lippert, Tobias Burkard, Franziska Markel, Volker Debus, Fridrike Stute, Anna Kamphues, Robert Dalla Pozza, Stefan Rupp, Maria B. Gonzalez y Gonzalez, Claudia Junge, Majed Kanaan, Kirstin Hoff, Anja Hanser, Sven Dittmann, Dominik Sebastian Westphal, Isabel Diebold, Sebastian Clauß, Stefanie Kessner, Marc‐Phillip Hitz, Kolja Becker, Stefan Kääb, Peter Ewert, Michael Hofbeck, Wolfgang Wällisch, Sven Dittrich, Anselm Uebing, Stephan Neumann, Jan‐Hendrik Nürnberg, Joachim Hebe, Rainer Kozlik‐Feldmann, Philipp Beerbaum, Gunter Kerst, Eric Schulze‐Bahr, Roman Gebauer, Gabriele Hessling, Cordula Maria Wolf   +35 more
wiley   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Atrial Repolarization as a Rare Mimicker of ST-Segment Elevation Myocardial Infarction: Revisiting T_a. [PDF]

JACC Case Rep
Chu J, Jakulla RS, Akrawinthawong K, Shah A.   +3 more
europepmc   +1 more source