Results 241 to 250 of about 105,162 (327)

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger   +4 more
wiley   +1 more source

Repolarization of Hepatocytes in Culture [PDF]

open access: bronze, 1997
Mark A. Talamini, B. Kappus, A L Hubbard
openalex   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti   +2 more
wiley   +1 more source

Effects of a single oral dose of sparfloxacin on ventricular repolarization in healthy volunteers [PDF]

open access: bronze, 1996
Jean‐Louis Démolis   +3 more
openalex   +1 more source

Transmural APD gradient synchronizes repolarization in the human left ventricular wall.

open access: yesCardiovascular Research, 2015
B. Boukens   +5 more
semanticscholar   +1 more source

Models of cardiomyocyte–non‐myocyte electrical interactions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Cardiomyocyte–non‐myocyte (CM–NM) electrotonic coupling. Left: conceptual contact‐based interactions between CM and other NM via connexin (Cx) proteins. Three basic scenarios are proposed: (i) ‘zero‐sided coupling’ where there are no electrical connections between CM and NM, (ii) ‘single‐sided coupling’ where NM are connected to ...
Ana Simon‐Chica   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy