Results 151 to 160 of about 21,330,318 (342)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Patient-reported reasons for the discontinuation of commonly used treatments for moderate to severe psoriasis

, 2012
Howa Yeung, Joy Wan, Abby S. Van Voorhees, Kristina Callis Duffin, Gerald G. Krueger, Robert E. Kalb, Jamie Weisman, Brian R. Sperber, Bruce A. Brod, Stephen M. Schleicher, Bruce F. Bebo, Daniel B. Shin, Andrea B. Troxel, Joel M. Gelfand   +13 more
openalex   +2 more sources

Mitral annular fibrous band—a unique morphological variant of a rare congenital mitral valve anomaly: a case report [PDF]

, 2022
Joseph Okafor, Anastasia Vamvakidou, Alexander R Lyons, Rajdeep Khattar   +3 more
openalex   +1 more source

Moment-Matching Polynomials

, 2013
We give a new framework for proving the existence of low-degree, polynomial approximators for Boolean functions with respect to broad classes of non-product distributions.
Klivans, Adam, Meka, Raghu
core   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Self-report of illicit substance use versus urine toxicology results from at-risk pregnant women

, 2010
Kimberly A. Yonkers, Heather B. Howell, Nathan Gotman, Bruce J. Rounsaville   +3 more
openalex   +2 more sources

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Pancreatic schwannoma: Case report and an updated 30-year review of the literature yielding 47 cases

, 2012
Toshiyuki Moriya
openalex   +2 more sources

Zhang et al. Diagnostic Pathology 2013, 8:157 [PDF]

Dendritic fibromyxolipoma in the right inguinal and perineum regions: a case report and review of the ...
Case Report
core