Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
OUTRAGEOUS VIOLATIONS: ENABLING STUDENTS TO INTERPRET NINETEENTH CENTURY NEWSPAPER REPORTS OF SEXUAL ASSAULT AND RAPE [PDF]
, 2014 This article is divided into two parts: the first highlights some of the difficulties and limitations for students and tutors who wish to explore the historiography of rape and sexual assault. In particular it addresses the problematic issue of accessing
Stevenson, KA
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Operational Manoeuvre Group: Operation SOHIL LARAM II, Kandahar Province, February 2008 [PDF]
, 2012 In February 2008 Regional Battle Group (South) in Afghanistan, based on The 1st Battalion, The Royal Gurkha Rifles supported by Canadian “enablers” and working with Afghan national security forces, conducted a mission known as Operation SOHIL LARAM II in
Maloney, Sean M.
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
The Philippine Center for Investigative Journalism (PCIJ) and ABS-CBN through the Prisms of Herman and Chomsky's "Propaganda Model": Duterte's Tirade against Media and vice versa [PDF]
, 2018 This paper is an attempt to localize Herman and Chomsky’s analysis of the commercial media and use this concept to fit in the Philippine media climate. Through the propaganda model, they introduced the five interrelated media filters which made possible ...
Mansueto, Menelito
core
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Doing Good and Looking Good in Global Humanitarian Reporting: Is Philanthrojournalism good news? [PDF]
, 2018 This chapter investigates if and how a private donor’s apparent motivation to ‘look good’ – or to generate symbolic capital – interacts with a news organization’s ability to ‘do good’ by producing public service content.
Bunce, M., Scott, M., Wright, K.
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source