Results 111 to 120 of about 4,208,353 (305)

Westward Spread of Echinococcus multilocularis in Foxes, France, 2005–2010

open access: yesEmerging Infectious Diseases, 2012
During 2005–2010, we investigated Echinococcus multilocularis infection within fox populations in a large area in France. The parasite is much more widely distributed than hitherto thought, spreading west, with a much higher prevalence than previously ...
Benoît Combes   +9 more
doaj   +1 more source

Intonation in Speech and Thought Reporting

open access: yesPoetica
Abstract Directly reported speech and thought are not only deictically and syntactically, but also prosodically less well integrated with the quotative expression than indirect reports. Though not an established result of the longstanding linguistic and philosophical scrutiny of the modes of speech and thought reporting, it was yet something Thomas ...
openaire   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Phase mixing of propagating Alfven waves in a stratified atmosphere: Solar spicules

open access: yes, 2012
Alfvenic waves are thought to play an important role in coronal heating and solar wind acceleration. Recent observations by Hinode/SOT showed that the spicules mostly exhibit upward propagating high frequency waves. Here we investigate the dissipation of
Altafi-Mehrabani, H.   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Prevalence and Use of Fitness Tracking Devices within a College Community [PDF]

open access: yes, 2017
Purpose: Wearable devices for tracking health and fitness related activities are thought to motivate individuals to participate in regular exercise. The purpose of this study was to examine the frequency of these wearable fitness tracking devices in a ...
Jones, Ellie K.   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Aspects of the washout of salmonid eggs. 4. Effects of a standard mechanical shock, applied at different stage of development, upon survival and development of eggs of brown trout (Salmo trutta L.) [PDF]

open access: yes, 1985
It is generally accepted by fish culturists that salmonid eggs are sensitive to mechanical shock and that the sensitivity varies with the stage of development of the eggs.
Crisp, D.T., Robson, S.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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