Results 51 to 60 of about 4,208,353 (305)

Glutamine in critical care:current evidence from systematic reviews [PDF]

, 2006
Glutamine, the most abundant amino acid in the body, is thought to become conditionally essential in critical illness. Some of the important roles for glutamine are as a carrier for inter-organ N, a preferred fuel for enterocytes and cells of the immune ...
Alison Avenell, Brantley, Déchelotte, Griffiths, Jacobi, Klek, Nitta, Ziegler   +7 more
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Questioning the rise of gelatinous zooplankton in the World's oceans [PDF]

, 2012
During the past several decades, high numbers of gelatinous zooplankton species have been reported in many estuarine and coastal ecosystems. Coupled with media-driven public perception, a paradigm has evolved in which the global ocean ecosystems are ...
Acuña, Alenka Malej, Atkinson, Beaglehole, Brodeur, Brodeur, Butterfield, Carlos M. Duarte, Cathy H. Lucas, Chen, Claudia E. Mills, Condon, Condon, Costello, Dakin, Daly, Daryanabard, Dawson, Dong, Ducklow, Edwards, Eiane, Gaillard, Galigher, Gand, Gorokhova, Goy, Graham, Grassle, Hagadorn, Hamner, Hamner, Herdman, Hermes Mianzan, Jackson, Jennifer E. Purcell, Kelly L. Robinson, Kelly R. Sutherland, Kogovšek, Kott, Kylie A. Pitt, Laurence P. Madin, Lavaniegos, Lotan, Lynam, Lynam, Macgillivray, Madin, Martin, Martin, Mary Beth Decker, Mayer, Michael N Dawson, Mills, Mills, Mills, Mills, Nel, Parsons, Pauly, Pauly, Pauly, Pickerill, Purcell, Péron, Quoy, Richardson, Rigby, Robert H. Condon, Russell, Russell, Sheard, Shin-ichi Uye, Stasinska, Stefan Gelcich, Steven H.D. Haddock, Strathmann, Sutherland, Uye, Uye, Vinogradov, William M. Graham   +81 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Cognitive complaint inversely associated to UHR transition

Schizophrenia Research: Cognition
The aim of this study was to identify the impact of staging on a six-months transition in Ultra-High Risk (UHR) youth.Subjects were enrolled at assessment; evolution was monitored for six months. Clinical determinants (unusual thought content, perceptual
Mirvat Hamdan-Dumont, Laurent Lecardeur, Marine Habert, Jérémy Couturas, Mireille Okassa, Aurélie Lacroix, Benjamin Calvet   +6 more
doaj   +1 more source

Detecting Temporal Cognition in Text: Comparison of Judgements by Self, Expert and Machine

Frontiers in Psychology, 2018
Background: There is a growing research focus on temporal cognition, due to its importance in memory and planning, and links with psychological wellbeing.
Erin I. Walsh, Janie Busby Grant
doaj   +1 more source

Giving Miss Marple a makeover : graduate recruitment, systems failure and the Scottish voluntary sector [PDF]

, 2010
The voluntary sector in Scotland, as across the globe, is becoming increasingly business like. Resultantly, there is an increasing demand for graduates to work in business and support functions. In Scotland, however, despite an oversupply of graduates in
ATA Management., Barnard, J., Bates, P., Bates, P., Chris Warhurst, Dennis Nickson, Elias, P., Felstead, A., Futureskills Scotland., Herriot, P., Higher Education Statistics Authority., Higher Education Statistics Authority., Keep, E., Mason, G., Meyer, M., Munro, S., Nickson, D., Perryman, S., Perryman, S., Scott. A. Hurrell, Scottish Government., Shah, R., Tierney, T.J., Wilding, K., Wilding, K., Zebra Square.   +25 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Cognitive, behavioral, and autonomic correlates of mind wandering and perseverative cognition in major depression [PDF]

, 2014
Autonomic dysregulation has been hypothesized to play a role in the relationships between psychopathology and cardiovascular risk. An important transdiagnostic factor that has been associated with autonomic dysfunction is perseverative cognition (PC ...
Cristina eOttaviani, David eShapiro, Ian eCook, Leila eShahabi, Michelle eAbrams, Mika eTarvainen, Mika eTarvainen   +6 more
core   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source