Results 151 to 160 of about 5,310,133 (264)
Reporting rates of topped-out merit-based incentive payment system (MIPS) quality measures, 2017-2023. [PDF]
Chung Y, Nicola LP, Rula EY.
europepmc +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
This research paper analyzes the impact of women’s empowerment (WE) on vulnerability to climate change (VCC) in South Asian countries from 1995-2023.
Bushra Mushtaq, Muhammad Afzal
doaj
Mapping and Quality Appraisal of Artificial Intelligence Preferential Reporting Checklists, Items, Guidelines, and Consensus in Healthcare: An Altmetric, Bibliometric, and Systematic Review. [PDF]
Vinay V +5 more
europepmc +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Mapping the landscape of concept analysis in nursing and auditing reporting completeness: a scoping review protocol. [PDF]
Ge J +6 more
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

