Results 151 to 160 of about 2,568,286 (273)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

US Virgin Islands Launches Modernized NBS 7 Disease Surveillance System to Transform Public Health: Implementation Report. [PDF]

JMIR Med Inform
Cranford HM, Pietka T, de Wilde L, Lawrence M, Ekpo LL, Ellis EM.   +5 more
europepmc   +1 more source

Report [PDF]

Datenschutz und Datensicherheit - DuD, 2020
openaire   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Evaluation du cadre pour l'organisation des élections / Democracy Reporting International

, 2007
unknown
core   +1 more source

Trends of Voluntary Internet Reporting in Croatia: Analysis for the Period 2005 - 2007 [PDF]

During the last decade a large number of scientific papers analyzed Internet reporting of listed companies, but research is still very limited in the emerging markets like Croatia. Therefore, this paper is aimed to analyze voluntary Internet reporting of
Ivica Pervan
core  

Women's Empowerment and Vulnerability to Climate Change: An Econometric Analysis of South Asian Countries

NUST Journal of Social Sciences and Humanities
This research paper analyzes the impact of women’s empowerment (WE) on vulnerability to climate change (VCC) in South Asian countries from 1995-2023.
Bushra Mushtaq, Muhammad Afzal
doaj  

Predicting Factors Affecting the Reporting of Medical Errors by Nurses Using the Theory of Planned Behavior: A Study in Iran. [PDF]

Health Serv Insights
Izadi O, Raeyat Mohtashami A, Delavari S, Nikmaram M, Ravangard R.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Comparative post-marketing reporting signals of elagolix and myfembree in endometriosis: a FAERS pharmacovigilance study. [PDF]

Front Pharmacol
Bai M, Shen S, Chen JY.
europepmc   +1 more source