Results 131 to 140 of about 1,240,159 (279)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Pharmacy Guidelines PHC Remote

, 2018
The Pharmacy Guidelines section includes:;Section 250 NT Medicines, Poisons and Therapeutic Goods Act PHC Remote Guideline;Cold Chain PHC Remote Guideline; Disposal of Unwanted Medicines Following an Emergency / Disaster Event PHC Remote Guideline;Dose ...

core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Diagnosis, staging and treatment of patients with oesophageal or oesophagogastric junction cancer [PDF]

, 2019
This National Clinical Guideline applies to adults (18 years or older) with newly diagnosed oesophageal or oesophagogastric junction (OGJ) cancer, or, those that have a suspected diagnosis of oesophageal or OGJ cancer in a hospital setting.
National Cancer Control Programme (NCCP) Guideline Development Group
core  

Quality of Case Reports and Adherence to the CARE (Case Report) Guidelines: Protocol for a Scoping Review [PDF]

Journal of Advanced Biomedical Sciences
Background & Objectives: The use of reporting guidelines aims to enhance the completeness and transparency of biomedical publications. The CARE guideline was developed in 2013 to assist researchers in improving the reporting of their case reports.
Abolfazl Taheri, payman Adibi, Marziye Saeedizadeh, Mojtaba Sabbagh Jafari, Alireza Rahimi, Alireza Abbasi   +5 more
doaj  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Improving the Transparency and Replicability of Consensus Methods: Respiratory Medicine as a Case Example

Pragmatic and Observational Research
Mark J Rolfe,1 Christopher C Winchester,1,2 Alison Chisholm,1 David B Price3,4 1Oxford PharmaGenesis, Oxford, UK; 2Green Templeton College, University of Oxford, Oxford, UK; 3Observational and Pragmatic Research Institute, Singapore, Singapore; 4Centre ...
Rolfe MJ, Winchester CC, Chisholm A, Price DB   +3 more
doaj  

A Systematic Review to Inform the Development of a Reporting Guideline for Concept Mapping Research. [PDF]

Methods Protoc, 2023
Pantha S, Jones M, Gartoulla P, Gray R.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source