Results 111 to 120 of about 3,002,470 (275)
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Measuring and Reporting on Sustainability Performance in the Cement Industry [PDF]
Corporate Social Responsibility (CSR) performance assessment and reporting has drawn a considerable amount of attention. In this context, the Global Reporting Initiative (GRI) has been among the first organizations to develop a framework for ...
Adrian VAIDA, Dan CANDEA
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Reducing Research Waste Through Good Reporting Practices
Journal of Epidemiology, 2016 Yasuyuki Okumura
doaj +1 more source
Reporting Guidelines in Implementation Science: Overview, Categorization and Future Directions
Xiehe Yixue ZazhiReporting guidelines are structured checklists for researchers to follow when reporting specific types of studies. As researches conducted in real-world settings to address practical issues, implementation research has stringent requirements for the ...
CHEN Xiaoshan +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Campbell Systematic ReviewsIntroduction The authors formed a small working group to modernize the Methodological Expectations for Campbell Collaboration Intervention Reviews (MECCIR).
Ariel M. Aloe +7 more
doaj +1 more source
Wanted: guidelines for reporting correlations
Advances in Physiology Education, 2009 Recently ([1][1]–[3][2]), there have been guidelines published for authors regarding what and how statistics should be reported when describing the differences between groups of observations. There seems to be a paucity of such guidance with respect to describing the correlation between groups ...
openaire +3 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source