The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Coronal native limb alignment: establishing reporting standards and aligning measurements of key angles. [PDF]
Scientific Committee from the Personalized Arthroplasty Society (PAS).
europepmc +1 more source
Correction to: The reporting standards of randomised controlled trials in leading medical journals between 2019 and 2020: a systematic review. [PDF]
McErlean M +3 more
europepmc +1 more source
Standardizing Brain Cancer Reporting
Markus, Glatzel, Ronald L, Hamilton
openaire +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Lack of harmonisation of greenhouse gases reporting standards and the methane emissions gap. [PDF]
Cenci S, Biffis E.
europepmc +1 more source
Delphi Consensus on Reporting Standards in Clinical Studies for Endovascular Treatment of Acute Iliofemoral Venous Thrombosis and Chronic Iliofemoral Venous Obstruction. [PDF]
Vedantham S +6 more
europepmc +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Reporting Standards for Economic Evaluations of Artificial Intelligence (AI) Interventions: A CHEERS Extension. [PDF]
Richardson M, Sagoo GS.
europepmc +1 more source
Artificial Intelligence Applications in Urology: Reporting Standards to Achieve Fluency for Urologists. [PDF]
Chen AB +6 more
europepmc +1 more source

